Zhang Yajing, Zhang Ting, Xia Xiaoshuang, Hu Yahui, Zhang Chao, Liu Ran, Yang Yun, Li Xin, Yue Wei
Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China.
Department of Neurology, The Second Hospital of Tianjin Medical University, Tianjin, China.
Front Aging Neurosci. 2023 Apr 4;15:1134187. doi: 10.3389/fnagi.2023.1134187. eCollection 2023.
To analyze the relationship between sleep quality, snoring symptoms, night shift and risk of stroke in Chinese population over 40 years old.
Based on the national screening and intervention program for high-risk population of stroke in 2016, 15,016 people completed the study of "the association between sleep and stroke," 58,696 people completed the snoring questionnaire, and 58,637 people completed the night shift questionnaire.
The proportion of coronary heart disease, hypertension, hyperlipidemia, diabetes, snoring, atrial fibrillation, stroke and high-risk group of stroke risk rating were higher in the group with poor sleep quality ( < 0.05). The proportion of high blood pressure, hyperlipidemia, diabetes, atrial fibrillation, transient ischemic attack (TIA), or high-risk group of stroke risk rating was higher in snoring group ( < 0.05). The body mass index (BMI), waist circumference, neck circumference, fasting blood glucose, triglyceride (TG), total cholesterol (TC), low density lipoprotein (LDL) and homocysteine (Hcy) levels in snoring group were higher than the non-snoring group, and high density lipoprotein (HDL) levels were lower ( < 0.05). People with TIA, high risk for stroke, and high blood pressure were higher in night shift workers than non-night shift workers ( < 0.05). The levels of BMI, fasting blood glucose, 2 h postprandial blood glucose, glycated hemoglobin, TG, TC, LDL, HDL and Hcy in night shift group were lower than the non-night shift group ( < 0.05).
Sleep quality, snoring and night shift might be related to the risk factors of stroke.
分析40岁以上中国人群睡眠质量、打鼾症状、夜班工作与中风风险之间的关系。
基于2016年全国脑卒中高危人群筛查与干预项目,15016人完成了“睡眠与中风关联”研究,58696人完成了打鼾问卷,58637人完成了夜班问卷。
睡眠质量差的人群中冠心病、高血压、高脂血症、糖尿病、打鼾、心房颤动、中风及中风风险评级高危组的比例更高(P<0.05)。打鼾组高血压、高脂血症、糖尿病、心房颤动、短暂性脑缺血发作(TIA)或中风风险评级高危组的比例更高(P<0.05)。打鼾组的体重指数(BMI)、腰围、颈围、空腹血糖、甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白(LDL)和同型半胱氨酸(Hcy)水平高于非打鼾组,高密度脂蛋白(HDL)水平更低(P<0.05)。夜班工作者中TIA、中风高危及高血压患者比例高于非夜班工作者(P<0.05)。夜班组的BMI、空腹血糖、餐后2小时血糖、糖化血红蛋白、TG、TC、LDL、HDL和Hcy水平低于非夜班组(P<0.05)。
睡眠质量、打鼾及夜班工作可能与中风的危险因素有关。