Gross J G
Department of Ophthalmology, University of South Carolina School of Medicine, Columbia.
Retina. 1992;12(4):341-5.
A 32-year-old man had unilateral visual loss, a gravitational layering of preretinal inflammatory cells in the macula (pseudohypopyon), subretinal infiltrates, and hemorrhagic vasculitis. The patient initially denied intravenous drug abuse. Apsergillus terreus was cultured from undiluted vitreous obtained from a diagnostic and therapeutic vitrectomy specimen. Intravitreal and subconjunctival injections of amphotericin B alone were successful treatment. To the author's knowledge, antemortem diagnosis and treatment of A. terreus-induced endophthalmitis has not been reported previously. This article describes the second case of aspergillar endophthalmitis successfully treated without adjunctive systemic antifungal therapy.
一名32岁男性出现单侧视力丧失，黄斑区视网膜前炎性细胞呈重力分层（假前房积脓）、视网膜下浸润及出血性血管炎。患者最初否认静脉药物滥用。从诊断性和治疗性玻璃体切割术标本获取的未稀释玻璃体中培养出土曲霉。单独玻璃体内及结膜下注射两性霉素B治疗成功。据作者所知，此前尚未有土曲霉所致眼内炎的生前诊断及治疗的报道。本文描述了第二例未联合全身抗真菌治疗而成功治愈的曲霉性眼内炎病例。
