Mur Villacampa M, Gimeno Esteras E, Guerrero Navarro L, Cabeza Lambán F, Sáinz Samitier R
Servicio de Aparato Digestivo, Hospital de Calatayud, Hospital Clínico de Zaragoza.
Rev Esp Enferm Dig. 1992 Nov;82(5):311-6.
The aim of this study was to evaluate the prevalence of Helicobacter pylori in 400 patients referred for upper digestive tract endoscopy. In our area it hasn't developed yet any epidemiologic study about this disease. Helicobacter pylori was observed in 281 of the 400 patients studied (70%). No significant differences by sex were found in the subjects analyzed. There was a rise in the percentage of positivities as age increased. Helicobacter pylori were positive in 74 of the 88 patients with chronic superficial gastritis (84.1%), in 53 of the 65 with chronic atrophic gastritis (81.5%), in 16 of the 25 with chronic atrophic gastritis and intestinal metaplasia (64%), in 49 of the 63 with gastric ulcer (77.8%), in 73 of the 85 with duodenal ulcer (85.9%), in 9 of the 24 patients with gastric carcinoma (37.5%), in 5 of the 19 with stump gastritis (26.3%), where as only a few Helicobacter pylori were found in 2 of the 31 histologically normal subjects (6.5%). These findings support the wiew that Helicobacter pylori may be etiologically related to chronic gastritis and peptic ulceration, even though their precise role still remains to be determined.
本研究旨在评估400例接受上消化道内镜检查患者的幽门螺杆菌感染率。在我们地区，尚未开展关于该疾病的任何流行病学研究。在400例研究患者中，有281例观察到幽门螺杆菌（70%）。在分析的受试者中，未发现性别之间存在显著差异。随着年龄增长，阳性率有所上升。88例慢性浅表性胃炎患者中有74例幽门螺杆菌呈阳性（84.1%），65例慢性萎缩性胃炎患者中有53例（81.5%），25例慢性萎缩性胃炎伴肠化生患者中有16例（64%），63例胃溃疡患者中有49例（77.8%），85例十二指肠溃疡患者中有73例（85.9%），24例胃癌患者中有9例（37.5%），19例残胃炎患者中有5例（26.3%），而31例组织学正常的受试者中只有2例发现少量幽门螺杆菌（6.5%）。这些发现支持了幽门螺杆菌可能在病因学上与慢性胃炎和消化性溃疡有关的观点，尽管它们的确切作用仍有待确定。
