Vessey M P, Villard-Mackintosh L, Painter R
Department of Public Health and Primary Care, Radcliffe Infirmary, Oxford, England.
Contraception. 1992 Oct;46(4):349-57. doi: 10.1016/0010-7824(92)90097-d.
There is evidence in the scientific literature that peptic ulceration occurs less frequently during pregnancy than at other times. This encouraged us to examine the pattern of hospitalisation for peptic ulcer in the Oxford-Family Planning Association contraceptive study. In total, 175 women in the study had been hospitalised for peptic ulcer; 105 had duodenal disease, 55 had gastric disease and 22 had disease of unspecified site (some had disease at more than one location). Hospitalisation for peptic ulcer increased with age, parity and cigarette smoking. In addition, hospitalisation was at a low rate during pregnancy and was not seen at all during the 12 months following delivery. There was no relationship between hospitalisation for peptic ulcer and total duration of oral contraceptive use. Likewise, there was no significant relationship with recency of oral contraceptive use, but the lowest rate of hospitalisation was in current users of the pill.
科学文献中有证据表明，消化性溃疡在孕期的发生率低于其他时期。这促使我们在牛津计划生育协会避孕研究中，对消化性溃疡的住院模式进行研究。该研究中，共有175名女性因消化性溃疡住院；其中105人患有十二指肠疾病，55人患有胃部疾病，22人患病部位不明（有些人不止一处患病）。消化性溃疡的住院率随年龄、产次和吸烟量增加而升高。此外，孕期住院率较低，产后12个月内则完全未见住院情况。消化性溃疡的住院情况与口服避孕药的总使用时长无关。同样，与近期口服避孕药的使用情况也无显著关系，但口服避孕药当前使用者的住院率最低。
