Favretto Laura
Milestone srl, Sorisole, BG, Italy.
Mol Divers. 2003;7(2-4):287-91. doi: 10.1023/b:modi.0000006906.47100.6b.
In the actual research world, the laboratory has different needs, correlated to the field and level of research. Some researchers work with small volumes, others with large ones; in homogeneous or heterogeneous conditions, with solvent or dry media; at normal pressure or under pressure. And if we look at the field of drug discovery, during the last decade combinatorial chemistry, along with combinatorial and parallel synthesis, has held a fundamental role. This technique is becoming more and more popular because it concerns the quick synthesis of a high number of compounds with pharmaceutical activity. In this context, the efficency of microwave heating to speed up chemical reactions matches perfectly the need of short and clean chemical reactions. Milestone's MicroSYNTH labstation combined with the microwave technology, satisfies the need of the various chemical research laboratories. In fact, the different accessories that can be fitted inside the multimode microwave cavity cover a large ramp of volume, from 2 ml to 500 ml, different values of pressure, from 1 to 50 bar, and give the possibility to reach temperature up to 250 degrees C. And this is not all, you can also choose to perform one reaction at a time or to perform parallel synthesis with Milestone's rotors for up to 24 reactions at the same time.
在实际的科研领域，实验室有不同的需求，这与研究领域和研究水平相关。一些研究人员处理少量样品，另一些则处理大量样品；在均相或非均相条件下，使用溶剂或干燥介质；在常压或加压条件下。如果我们看看药物研发领域，在过去十年中，组合化学以及组合和平行合成发挥了基础性作用。这项技术越来越受欢迎，因为它涉及快速合成大量具有药物活性的化合物。在这种背景下，微波加热加速化学反应的效率与短而清洁的化学反应需求完美契合。迈尔斯通公司的MicroSYNTH实验室工作站结合微波技术，满足了各类化学研究实验室的需求。事实上，可安装在多模微波腔体内的不同附件涵盖了从2毫升到500毫升的大体积范围、从1到50巴的不同压力值，并且能够达到高达250摄氏度的温度。而且不止如此，你还可以选择一次进行一个反应，或者使用迈尔斯通的转子同时进行多达24个反应的平行合成。
