肠球菌对环丙沙星的耐药性增强。
Increasing resistance of enterococci to ciprofloxacin.
作者信息
Schaberg D R, Dillon W I, Terpenning M S, Robinson K A, Bradley S F, Kauffman C A
机构信息
Division of Infectious Diseases, University of Michigan Medical School, Ann Arbor 48109.
出版信息
Antimicrob Agents Chemother. 1992 Nov;36(11):2533-5. doi: 10.1128/AAC.36.11.2533.
Abstract
We determined that resistance to ciprofloxacin has emerged in enterococci over the last 5 years in our hospital, mainly in strains demonstrating the phenotype of high-level gentamicin resistance. All high-level-gentamicin-resistant isolates from 1985 and 1986 were susceptible, whereas 24% of isolates from 1989 and 1990 were resistant to ciprofloxacin. Plasmid and genomic DNA typing showed at least six unique strains exhibiting resistance, but one type accounted for 80% of recent resistant isolates, suggesting a role for cross infection in the emergence of resistance.
摘要
我们确定，过去5年里我院肠球菌中出现了对环丙沙星的耐药性，主要出现在表现出高水平庆大霉素耐药表型的菌株中。1985年和1986年所有高水平庆大霉素耐药菌株均敏感，而1989年和1990年的分离株中有24%对环丙沙星耐药。质粒和基因组DNA分型显示至少有6种独特的耐药菌株，但其中一种类型占近期耐药分离株的80%，提示交叉感染在耐药性出现中起作用。
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本文引用的文献
1
High-level aminoglycoside-resistant enterococci. Colonization of nursing home and acute care hospital patients.
Arch Intern Med. 1987 Sep;147(9):1591-4. doi: 10.1001/archinte.147.9.1591.
2
In vitro activity of ciprofloxacin against gram-positive bacteria. An overview.
Am J Med. 1987 Apr 27;82(4A):33-9.
3
Enterococcal superinfection in patients treated with ciprofloxacin.接受环丙沙星治疗的患者发生肠球菌二重感染。
J Antimicrob Chemother. 1988 Jan;21(1):113-5. doi: 10.1093/jac/21.1.113.
4
Development of resistance in Pseudomonas aeruginosa to imipenem, norfloxacin, and ciprofloxacin during therapy: proof provided by typing with a DNA probe.
J Infect Dis. 1988 Apr;157(4):743-8. doi: 10.1093/infdis/157.4.743.
5
Identification of Streptococcus faecalis and Streptococcus faecium and susceptibility studies with newly developed antimicrobial agents.粪肠球菌和屎肠球菌的鉴定以及新型抗菌剂的药敏研究。
J Clin Microbiol. 1987 May;25(5):787-90. doi: 10.1128/jcm.25.5.787-790.1987.
6
Nosocomial infection by gentamicin-resistant Streptococcus faecalis. An epidemiologic study.耐庆大霉素粪肠球菌的医院感染。一项流行病学研究。
Ann Intern Med. 1987 May;106(5):687-91. doi: 10.7326/0003-4819-106-5-687.
7
High-level resistance to gentamicin in Streptococcus faecalis: risk factors and evidence for exogenous acquisition of infection.
J Infect Dis. 1986 Jun;153(6):1075-83. doi: 10.1093/infdis/153.6.1075.
8
High-level penicillin resistance among isolates of enterococci. Implications for treatment of enterococcal infections.肠球菌分离株中的高水平青霉素耐药性。对肠球菌感染治疗的影响。
Ann Intern Med. 1989 Apr 1;110(7):515-20. doi: 10.7326/0003-4819-110-7-515.
9
Enterococci highly resistant to penicillin and ampicillin: an emerging clinical problem?对青霉素和氨苄西林高度耐药的肠球菌：一个新出现的临床问题？
J Clin Microbiol. 1989 Sep;27(9):2091-5. doi: 10.1128/jcm.27.9.2091-2095.1989.
10
In vitro activities of quinolones against enterococci resistant to penicillin-aminoglycoside synergy.喹诺酮类药物对耐青霉素-氨基糖苷类协同作用肠球菌的体外活性。
Antimicrob Agents Chemother. 1989 Jan;33(1):71-7. doi: 10.1128/AAC.33.1.71.
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