Smokovitis A, Astrup T
J Neurosurg. 1978 Jun;48(6):1008-14. doi: 10.3171/jns.1978.48.6.1008.
Fibrinolytic activity (caused by a plasminogen activator) in the spinal cord was highest in the rat, lowest in the rabbit, and intermediate in the guinea pig; In all species the activity was highest in relation to the pia mater. The central spinal canal was active in the rat and the rabbit, but mostly inactive in the guinea pig. Foci of activity were more numerous in the gray matter than in the white matter corresponding to the greater vascularity of the former. In all species ability to inhibit plasmin was related mainly to the gray matter, with an additional area related to the dura mater. The high fibrinolytic activity of the spinal leptomeninges may play a role in the pathogenesis of hemorrhagic processes related to the spinal cord.
脊髓中的纤溶活性（由纤溶酶原激活物引起）在大鼠中最高，在兔中最低，在豚鼠中处于中间水平；在所有物种中，与软脑膜相关的活性最高。大鼠和兔的中央脊髓管有活性，但豚鼠的大多无活性。与灰质血管更丰富相对应，灰质中的活性灶比白质中的更多。在所有物种中，抑制纤溶酶的能力主要与灰质有关，还有一个与硬脑膜相关的额外区域。脊髓软脑膜的高纤溶活性可能在与脊髓相关的出血性过程的发病机制中起作用。
