Supèr Hans, van der Togt Chris, Spekreijse Henk, Lamme Victor A F
Netherlands Ophthalmic Research Institute, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands.
Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):3230-5. doi: 10.1073/pnas.0400433101. Epub 2004 Feb 17.
We continuously scan the visual world via rapid or saccadic eye movements. Such eye movements are guided by visual information, and thus the oculomotor structures that determine when and where to look need visual information to control the eye movements. To know whether visual areas contain activity that may contribute to the control of eye movements, we recorded neural responses in the visual cortex of monkeys engaged in a delayed figure-ground detection task and analyzed the activity during the period of oculomotor preparation. We show that approximately 100 ms before the onset of visually and memory-guided saccades neural activity in V1 becomes stronger where the strongest presaccadic responses are found at the location of the saccade target. In addition, in memory-guided saccades the strength of presaccadic activity shows a correlation with the onset of the saccade. These findings indicate that the primary visual cortex contains saccade-related responses and participates in visually guided oculomotor behavior.
我们通过快速或扫视眼动不断扫描视觉世界。此类眼动由视觉信息引导，因此，决定何时何地注视的动眼结构需要视觉信息来控制眼动。为了解视觉区域是否包含可能有助于控制眼动的活动，我们记录了参与延迟图形-背景检测任务的猴子视觉皮层中的神经反应，并分析了动眼准备期间的活动。我们发现，在视觉引导和记忆引导的扫视开始前约100毫秒，V1区中在扫视目标位置出现最强扫视前反应的地方，神经活动会增强。此外，在记忆引导的扫视中，扫视前活动的强度与扫视的开始存在相关性。这些发现表明，初级视觉皮层包含与扫视相关的反应，并参与视觉引导的动眼行为。
