Seregin Sergei V, Samokhvalov Evgeny I, Petrova Irina D, Vyshemirskii Oleg I, Samokhvalova Ekaterina G, Lvov Dmitry K, Gutorov Valery V, Tyunnikov Georgy I, Shchelkunov Sergei N, Netesov Sergei V, Petrov Vladimir S
State Research Center of Virology and Biotechnology "VECTOR", Koltsovo, Novosibirsk Region, 630559, Russia.
Virus Genes. 2004 Mar;28(2):187-93. doi: 10.1023/B:VIRU.0000016857.94136.89.
The data on the structure of the M genome segment of CCHF virus strains from Russia and Central Asia (Tajikistan) are presented. Data obtained have been compared with other available published sequences of the middle segment of strains from China, Nigeria, and Pakistan. It has been found that all the known strains can be divided into four genetic groups, based on the nucleotide sequence of the M genome segment and an amino acid sequence of the glycoprotein precursor it encodes, whereas VLG/TI29414 and STV/HU29223 strains from Russia form a separate group. The CCHF virus strain from Tajikistan, TADJ/HU8966, was genetically related to strains 7803 and 75024 from China, and together with these and the Nigerian IbAr 10200 strain, it forms another group.
本文展示了来自俄罗斯和中亚（塔吉克斯坦）的克里米亚-刚果出血热病毒（CCHF病毒）毒株M基因组片段的结构数据。已将所得数据与来自中国、尼日利亚和巴基斯坦的毒株中间片段的其他已发表序列进行了比较。基于M基因组片段的核苷酸序列及其编码的糖蛋白前体的氨基酸序列，已发现所有已知毒株可分为四个遗传组，而来自俄罗斯的VLG/TI29414和STV/HU29223毒株形成一个单独的组。来自塔吉克斯坦的CCHF病毒毒株TADJ/HU8966与来自中国的7803和75024毒株在遗传上相关，并且与这些毒株以及尼日利亚的IbAr 10200毒株一起形成了另一个组。
