Qi Qing-hui, Wang Jian, Hui Jian-feng
General Hospital of Tianjin Medical University, Tianjin 300052.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004 Jan;24(1):21-4.
To study the therapeutic effect and mechanism of Dachengqi granule (DCQG) on some digestive motility disturbed diseases.
Gastroduodenojejunal manometry, electrogastrography (EGG), RIA of motilin and orocecal transit time test were applied to directly observe the effect of DCQG on human gastrointestinal motility.
DCQG could significantly improve the postoperational EGG disorder, elevate the amplitude and time of migrating motor complex (MMC) phase III, prevent gastrointestinal reversed peristalsis, increase the blood level of motilin, decrease the orocecal transit time, and promote the recovery of gastrointestinal motility.
DCQG is an effective digestive kinetic agent, which could be medicated conveniently in treating digestive motility disturbed diseases.
研究大承气颗粒(DCQG)对某些消化运动紊乱性疾病的治疗作用及机制。
采用胃十二指肠空肠测压法、胃电图(EGG)、胃动素放射免疫分析法(RIA)及口盲肠转运时间试验,直接观察DCQG对人体胃肠动力的影响。
DCQG能显著改善术后EGG紊乱,提高移行性运动复合波(MMC)Ⅲ相的振幅和时间,防止胃肠逆蠕动,提高胃动素血药浓度,缩短口盲肠转运时间,促进胃肠动力恢复。
DCQG是一种有效的促消化动力药物,治疗消化运动紊乱性疾病用药方便。