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[局部晚期头颈部癌患者超分割加速放疗联合顺铂同步给药的剂量探索性研究]

[Dose-finding study for hyperfractionated, accelerated radiotherapy plus simultaneous carboplatin administration in patients with locoregionally advanced head and neck cancer].

作者信息

Kehrl W, Brockmann W P, Zschaber R, Hartwein J

机构信息

HNO-Klinik, Universitäts-Krankenhauses Hamburg-Eppendorf.

出版信息

Laryngorhinootologie. 1992 Jul;71(7):370-4. doi: 10.1055/s-2007-997317.

DOI:10.1055/s-2007-997317
PMID:1497771
Abstract

Therapy of large inoperable squamous cell-carcinomas of the head and neck is considerably problemful. Combined simultaneous radio-chemotherapy with carboplatin and radiotherapy with hyperfractionated accelerated radiation is small effective than conventional monofractionated radiotherapy alone and may reduce side effects. Aim of the following study was dosage optimisation of the applicated carboplatin.

摘要

头颈部大型不可手术切除的鳞状细胞癌的治疗存在相当大的问题。卡铂同步放化疗与超分割加速放疗联合使用的效果比单纯传统单次分割放疗小，且可能减少副作用。以下研究的目的是优化卡铂的应用剂量。

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