Sweeney Louise C, Dave Jayshree, Chambers Philip A, Heritage John
School of Biochemistry and Microbiology, University of Leeds, Leeds LS2 9JT, UK.
J Antimicrob Chemother. 2004 Apr;53(4):567-76. doi: 10.1093/jac/dkh137. Epub 2004 Feb 25.
This review examines the contribution dental prescribing makes to the selection of antibiotic resistance in bacteria of the oral flora. The antibiotics commonly used in dental prescribing in the UK are discussed, together with the problems of resistance in members of the oral flora. The antibiotic prescribing habits of general dental practitioners are then reviewed with respect to therapeutic prescriptions and those drugs that are prescribed prophylactically. Not all antibiotic prescriptions for dental problems are written by dentists; prescribing outside the dental profession is also considered. The review then considers the support available to dentists from clinical diagnostic microbiology laboratories. It concludes that better use of diagnostic services, surveillance and improvements in dental education are required now to lessen the impact of antibiotic resistance in the future.
本综述探讨了牙科处方对口腔菌群中细菌抗生素耐药性选择的影响。文中讨论了英国牙科处方中常用的抗生素，以及口腔菌群成员的耐药性问题。接着回顾了普通牙科医生在治疗性处方和预防性用药方面的抗生素处方习惯。并非所有牙科问题的抗生素处方都是由牙医开具的，非牙科专业的处方情况也在考虑范围内。该综述还考虑了临床诊断微生物实验室为牙医提供的支持。结论是，现在需要更好地利用诊断服务、监测并改进牙科教育，以减轻未来抗生素耐药性的影响。
