Zhang Xing-ru, Cai Rui-xia, Wang Bao-hua, Li Qing-song, Liu Ye-xiang, Xu Yan
Department of Ophthalmology, Affiliated Pu-tuo Hospital to Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.
Zhonghua Yan Ke Za Zhi. 2004 Jan;40(1):37-9.
To observe the histopathological change of conjunctivochalasis.
Conjunctival tissue was collected from 17 patients with conjunctivochalasis and 15 simple cataract patients. By HE/Verhoeff elastic fiber staining, the histopathological changes of conjunctival tissues in the patients were compared with those of simple cataract patients.
The pathologic changes in conjunctivochalasis patients were characterized with hyperplasia of squamous epithelium with parakeratosis, pigmentation with different level in basal cell, hemorrhage, edema of stroma, infiltration of lymphocyte and plasmocyte. The elastic fiber layer was decreased.
There was hyperplasia of conjunctival epithelium, decrease of elastic fiber and chronic inflammation in patients with conjunctivochalasis. The decrease of elastic fiber should be considered as major cause of the changes of conjunctiva.
观察结膜松弛症的组织病理学变化。
收集17例结膜松弛症患者及15例单纯白内障患者的结膜组织。通过苏木精-伊红（HE）/韦尔霍夫弹性纤维染色，将患者结膜组织的组织病理学变化与单纯白内障患者进行比较。
结膜松弛症患者的病理变化表现为鳞状上皮增生伴不全角化，基底细胞不同程度色素沉着，出血，基质水肿，淋巴细胞和浆细胞浸润。弹性纤维层减少。
结膜松弛症患者存在结膜上皮增生、弹性纤维减少及慢性炎症。弹性纤维减少应被视为结膜变化的主要原因。
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