糖酵解酶与细胞骨架的关联。
Association of glycolytic enzymes with the cytoskeleton.
作者信息
Knull H R, Walsh J L
机构信息
Department of Biochemistry and Molecular Biology, University of North Dakota School of Medicine, Grand Forks 58202.
出版信息
Curr Top Cell Regul. 1992;33:15-30. doi: 10.1016/b978-0-12-152833-1.50007-1.
Abstract
The diverse physical associations of the glycolytic enzymes with structural components of the cell suggest that the glycolytic enzymes are not entirely soluble in the cell. The relatively low affinities of the associations are likely responsible for the apparently transient interactions. The binding phenomenon is suggested to regulate metabolism through changes in enzymatic activity and facilitates localized enrichment of the enzymes.
摘要
糖酵解酶与细胞结构成分的多种物理关联表明，糖酵解酶在细胞中并非完全可溶。这些关联的相对低亲和力可能是导致明显短暂相互作用的原因。有人认为这种结合现象通过酶活性的变化来调节代谢，并促进酶的局部富集。
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