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猫肠道淋巴瘤免疫表型的潜在预后意义:一项初步研究。

The possible prognostic significance of immunophenotype in feline alimentary lymphoma: a pilot study.

作者信息

Patterson-Kane J C, Kugler B Perrins, Francis K

机构信息

Department of Pathology and Infectious Diseases, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA, UK.

出版信息

J Comp Pathol. 2004 Feb-Apr;130(2-3):220-2. doi: 10.1016/j.jcpa.2003.09.008.

Abstract

Twenty-three retrospective biopsy specimens from feline intra-abdominal lymphomas including tumours affecting the gastrointestinal tract, mesenteric lymph nodes, liver and spleen were immunohistochemically labelled with monoclonal antibodies to CD79a (B-cell phenotype) and CD3 (T-cell phenotype). Positive labelling occurred in 15 (65%) and 6 (26%) of the tumours, respectively. No statistically significant relationship was found between tumour cell immunophenotype and age, breed, or gender. There was no significant difference in survival time between the two immunophenotypes, based on the 16 cats for which this information was available.

摘要

对23份来自猫腹腔淋巴瘤的回顾性活检标本进行免疫组化标记,这些淋巴瘤包括影响胃肠道、肠系膜淋巴结、肝脏和脾脏的肿瘤,使用针对CD79a(B细胞表型)和CD3(T细胞表型)的单克隆抗体。分别在15例(65%)和6例(26%)肿瘤中出现阳性标记。未发现肿瘤细胞免疫表型与年龄、品种或性别之间存在统计学上的显著关系。根据可获得该信息的16只猫,两种免疫表型之间的生存时间没有显著差异。

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