一种犬细小病毒突变株正在意大利传播。
A canine parvovirus mutant is spreading in Italy.
作者信息
Martella Vito, Cavalli Alessandra, Pratelli Annamaria, Bozzo Giancarlo, Camero Michele, Buonavoglia Domenico, Narcisi Donato, Tempesta Maria, Buonavoglia Canio
机构信息
Department of Animal Health and Wellbeing, University of Bari, Bari, Italy.
出版信息
J Clin Microbiol. 2004 Mar;42(3):1333-6. doi: 10.1128/JCM.42.3.1333-1336.2004.
Abstract
By antigenic and genetic characterization of canine parvovirus type 2 (CPV-2) strains collected in 2001 and 2002 in Italy, it was possible to observe the spread of viruses with an unusual mutation, Glu-426, affecting a major antigenic epitope of CPV-2. Out of 67 strains analyzed, 49 (73.13%) were characterized as CPV-2a, 6 (8.95%) were characterized as CPV-2b, and 12 (17.91%) were characterized as the Glu-426 mutant.
摘要
通过对2001年和2002年在意大利收集的2型犬细小病毒（CPV-2）毒株进行抗原和基因特征分析，得以观察到带有异常突变Glu-426的病毒传播情况，该突变影响CPV-2的一个主要抗原表位。在分析的67个毒株中，49个（73.13%）被鉴定为CPV-2a，6个（8.95%）被鉴定为CPV-2b，12个（17.91%）被鉴定为Glu-426突变体。
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