Suppr超能文献

不同准直系统直线加速器放射治疗中光中子场的蒙特卡罗模拟。

Monte Carlo simulation of the photoneutron field in linac radiotherapy treatments with different collimation systems.

作者信息

Zanini A, Durisi E, Fasolo F, Ongaro C, Visca L, Nastasi U, Burn K W, Scielzo G, Adler J O, Annand J R M, Rosner G

机构信息

INFN Turin, Via P Giuria 1, 10125 Turin, Italy.

出版信息

Phys Med Biol. 2004 Feb 21;49(4):571-82. doi: 10.1088/0031-9155/49/4/008.

Abstract

Bremsstrahlung photon beams produced by linac accelerators are currently the most commonly used method of radiotherapy for tumour treatments. When the photon energy exceeds 10 MeV the patient receives an undesired dose due to photoneutron production in the accelerator head. In the last few decades, new sophisticated techniques such as multileaf collimators have been used for a better definition of the target volume. In this case it is crucial to evaluate the photoneutron dose produced after giant dipole resonance (GDR) excitation of the high Z materials (mainly tungsten and lead) constituting the collimator leaves in view of the optimization of the radiotherapy treatment. A Monte Carlo approach has been used to calculate the photoneutron dose arising from the GDR reaction during radiotherapy with energetic photon beams. The simulation has been performed using the code MCNP4B-GN which is based on MCNP4B, but includes a new routine GAMMAN to model photoneutron production. Results for the facility at IRCC (Istituto per la Ricerca e la Cura del Cancro) Candiolo (Turin), which is based on 18 MV x-rays from a Varian Clinac 2300 C/D, are presented for a variety of different collimator configurations.

摘要

直线加速器产生的轫致辐射光子束是目前肿瘤治疗中最常用的放射治疗方法。当光子能量超过10兆电子伏特时,由于加速器头部产生光中子,患者会接受不必要的剂量。在过去几十年中,诸如多叶准直器等新的精密技术已被用于更好地确定靶体积。在这种情况下,鉴于放射治疗的优化,评估构成准直器叶片的高Z材料(主要是钨和铅)在巨偶极共振(GDR)激发后产生的光中子剂量至关重要。已采用蒙特卡罗方法来计算高能光子束放射治疗期间GDR反应产生的光中子剂量。使用基于MCNP4B的代码MCNP4B - GN进行了模拟,但该代码包含一个用于模拟光中子产生的新程序GAMMAN。给出了位于都灵坎迪奥洛的IRCC(肿瘤研究与治疗机构)设施的结果,该设施基于瓦里安Clinac 2300 C/D产生的18兆伏X射线,涵盖了各种不同的准直器配置。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验