阿氏疏螺旋体和加氏疏螺旋体所致游走性红斑的比较。
Comparison of erythema migrans caused by Borrelia afzelii and Borrelia garinii.
作者信息
Logar M, Ruzić-Sabljić E, Maraspin V, Lotric-Furlan S, Cimperman J, Jurca T, Strle F
机构信息
Dept. of Infectious Diseases, University Medical Centre, Japljeva 2, SLO-1525, Ljubljana, Slovenia.
出版信息
Infection. 2004 Feb;32(1):15-9. doi: 10.1007/s15010-004-3042-z.
BACKGROUND
We compared epidemiological and clinical characteristics of patients with erythema migrans (EM) caused by Borrelia afzelii and Borrelia garinii.
PATIENTS AND METHODS
200 consecutive adult patients with B. afzelii isolated from the skin lesion and 53 consecutive adult patients with EM caused by B. garinii qualified for the present study.
RESULTS
Comparison of the two groups revealed several distinctions. Patients with EM caused by B. garinii were older, had their skin lesions more often located on the trunk but less often on extremities, had shorter incubation and faster evolution of EM, more often reported associated local and certain systemic symptoms, had abnormal liver function test results more often and were more frequently seropositive.
CONCLUSION
Early localized Lyme borreliosis caused by B. afzelii and B. garinii has distinct epidemiological and clinical characteristics. Clinical features of EM depend upon the genospecies of Borrelia burgdorferi sensu lato causing the illness.
背景
我们比较了阿氏疏螺旋体和伽氏疏螺旋体引起的游走性红斑（EM）患者的流行病学和临床特征。
患者与方法
本研究纳入了200例连续从皮肤病变中分离出阿氏疏螺旋体的成年患者以及53例连续由伽氏疏螺旋体引起EM的成年患者。
结果
两组比较显示出若干差异。伽氏疏螺旋体引起EM的患者年龄较大，皮肤病变更多见于躯干但较少见于四肢，EM的潜伏期较短且进展较快，更常报告伴有局部和某些全身症状，肝功能检查结果异常更为常见，血清学阳性更为频繁。
结论
阿氏疏螺旋体和伽氏疏螺旋体引起的早期局限性莱姆病具有不同的流行病学和临床特征。EM的临床特征取决于引起该病的狭义伯氏疏螺旋体的基因种。
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