Holtkamp K, Konrad K, Müller B, Heussen N, Herpertz S, Herpertz-Dahlmann B, Hebebrand J
Department of Child and Adolescent Psychiatry and Psychotherapy, Technical University of Aachen, Germany.
Int J Obes Relat Metab Disord. 2004 May;28(5):685-9. doi: 10.1038/sj.ijo.0802623.
Epidemiological studies suggest that adiposity in children may be associated with a reduced level of physical activity. Children with Attention-Deficit/Hyperactivity Disorder (ADHD) are physically hyperactive as of early childhood and have been shown to exhibit higher levels of motor activity than normal. The aim of our study was to assess if the prevalence of overweight and obesity is lower in a population of boys with ADHD in comparison with the German healthy male reference population of the same age.
Patients were investigated from 1999 until 2001 upon referral to the inpatient and outpatient unit of the Department of Child and Adolescent Psychiatry of the University of Aachen.
A total of 97 male patients (mean age 10+/-2 y) with a diagnosis of ADHD according the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV), who were free of potentially orexigenic medication and who had no further comorbid diagnosis apart from conduct disorder.
BMI standard deviation scores (BMI-SDS) were calculated and compared to age-adapted reference value of the German population.
Patients' mean BMI-SDS was significantly higher than the age-adapted reference values of the German population (P=0.038). Our sample included significantly more subjects than expected with a BMI > or =90th percentile (19.6%, P<0.001) and > or =97th percentile (7.2%, P=0.007).
Surprisingly, being 'hyperactive' in the sense of the DSM-IV diagnosis of ADHD does not prevent the development or persistence of overweight and obesity in children. The examination of these children might be a helpful approach in the investigation of the relationship between obesity and its contributing psychological and behavioural factors.
流行病学研究表明，儿童肥胖可能与身体活动水平降低有关。注意力缺陷多动障碍（ADHD）儿童从幼儿期就表现为身体多动，且已被证明比正常儿童表现出更高水平的运动活动。我们研究的目的是评估与同年龄的德国健康男性参考人群相比，患有ADHD的男孩群体中超重和肥胖的患病率是否更低。
1999年至2001年期间，对转诊至亚琛大学儿童与青少年精神病学系住院部和门诊部的患者进行了调查。
共有97名男性患者（平均年龄10±2岁），根据《精神疾病诊断与统计手册》（DSM - IV）诊断为ADHD，未使用可能导致食欲增加的药物，除品行障碍外无其他共病诊断。
计算体重指数标准差分数（BMI - SDS），并与德国人群的年龄适配参考值进行比较。
患者的平均BMI - SDS显著高于德国人群的年龄适配参考值（P = 0.038）。我们的样本中BMI≥第90百分位数（19.6%，P < 0.001）和≥第97百分位数（7.2%，P = 0.007）的受试者明显多于预期。
令人惊讶的是，从DSM - IV诊断的ADHD意义上讲的“多动”并不能预防儿童超重和肥胖的发生或持续。对这些儿童的检查可能是研究肥胖与其相关心理和行为因素之间关系的一种有用方法。
