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注意缺陷多动障碍男孩的超重与基础代谢率

Overweight and basal metabolic rate in boys with attention-deficit/hyperactivity disorder.

作者信息

Hubel R, Jass J, Marcus A, Laessle R G

机构信息

Department of Psychology, University of Trier, 54286 Trier, Germany.

出版信息

Eat Weight Disord. 2006 Sep;11(3):139-46. doi: 10.1007/BF03327559.

DOI:10.1007/BF03327559
PMID:17075241
Abstract

We investigated a possible association between attention-deficit/hyperactivity disorder (ADHD) and overweight by measuring weight status and energy expenditure (basal metabolic rate, BMR) in 39 ADHD-boys with hyperactivity (mixed hyperactive/impulsive and inattentive or predominantly hyperactive/impulsive) and 30 healthy boys. The age range for the total group was 8-14 years. Weight and height were measured by a calibrated scales and stadiometer. Body mass index standard deviation scores (BMI-SDS) were calculated. BMR was determined by indirect calorimetry. Significant differences were obtained between the ADHD- and the control-group, but not between ADHD-subgroups. Both BMI-SDS and BMR were higher in the group of ADHD-boys, whereby the differences were more marked when they were older. More overweight and obese subjects were found in the ADHD-sample. Impulsive behavior in ADHD-boys with hyperactivity may lead to an increased food intake, which is then likely to overcompensate the heightened energy expenditure.

摘要

我们通过测量39名患有多动症状的注意力缺陷多动障碍(ADHD)男孩(混合性多动/冲动与注意力不集中型或主要为多动/冲动型)和30名健康男孩的体重状况及能量消耗(基础代谢率,BMR),研究了ADHD与超重之间可能存在的关联。整个研究组的年龄范围为8至14岁。体重和身高通过校准过的秤和身高计进行测量。计算体重指数标准差分数(BMI-SDS)。BMR通过间接测热法测定。ADHD组与对照组之间存在显著差异,但ADHD亚组之间无差异。ADHD男孩组的BMI-SDS和BMR均较高,年龄较大时差异更为明显。在ADHD样本中发现更多超重和肥胖的受试者。患有多动症状的ADHD男孩的冲动行为可能导致食物摄入量增加,进而可能过度补偿增加的能量消耗。

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Childhood obesity and attention deficit/hyperactivity disorder: a newly described comorbidity in obese hospitalized children.儿童肥胖与注意力缺陷/多动障碍:肥胖住院儿童中一种新发现的共病情况。
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The NK1R-/- mouse phenotype suggests that small body size, with a sex- and diet-dependent excess in body mass and fat, are physical biomarkers for a human endophenotype with vulnerability to attention deficit hyperactivity disorder.NK1R基因敲除小鼠的表型表明,体型小,伴有与性别和饮食有关的体重和脂肪过多,是人类具有注意力缺陷多动障碍易感性内表型的生理生物标志物。
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