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阻塞性睡眠呼吸暂停低通气综合征患儿根据呼吸暂停低通气指数(AHI)得分的颅面差异:39例患者的头影测量研究

Craniofacial differences according to AHI scores of children with obstructive sleep apnoea syndrome: cephalometric study in 39 patients.

作者信息

Ozdemir Hüseyin, Altin Remzi, Söğüt Ayhan, Cinar Fikret, Mahmutyazicioğlu Kamran, Kart Levent, Uzun Lokman, Davşanci Halit, Gündoğdu Sadi, Tomaç Nazan

机构信息

Department of Radiology, Medical School, Zonguldak Karaelmas University, Kozlu, 67600 Zonguldak, Turkey.

出版信息

Pediatr Radiol. 2004 May;34(5):393-9. doi: 10.1007/s00247-004-1168-x. Epub 2004 Mar 16.

Abstract

BACKGROUND

Cephalometry is useful as a screening test for anatomical abnormalities in patients with obstructive sleep apnoea syndrome (OSAS).

OBJECTIVE

To evaluate comprehensively the cephalometric features of children with OSAS, with or without adenotonsillar hypertrophy, and to elucidate the relationship between cephalometric variables and apnoea-hypopnoea index (AHI) severity.

MATERIALS AND METHODS

The study population consisted of 39 children, aged 4-12 years, with OSAS. Cephalometry was analysed using 11 measurements of the bony structures, their relationships and the size of the airways. Additionally, adenoid and tonsillar hypertrophy were graded.

RESULTS

Cranial base angles (BaSN and BaSPNS) were found to correlate with increasing levels of AHI scores (P<0.001). Protrusion of the maxilla (SNA) and mandible (SNB) did not correlate with AHI scores (P>0.05). The length of the mandibular plane (GnGo) and the minimal posterior airway space (MPAS) were inversely correlated with AHI scores (P<0.001). There was positive correlation between MPAS and GnGo (r=0.740, P<0.001), and negative correlation between MPAS and gonial angle (ArGoGn) (r=-0.541, P<0.001). There was significant correlation between cephalometric data and adenotonsillar hypertrophy concerning BaSN, BaSPNS, ArGoGn, GnGoH, BaN-GnGo, MPAS, GnGO and MPH (P<0.001).

CONCLUSIONS

There is significant correlation between cephalometric data and AHI score severity in children with OSAS. Adenotonsillar hypertrophy affects the cephalometric measurements adversely. The study clearly mandates the institution of early and effective therapy of adenotonsillar hypertrophy in children with OSAS.

摘要

背景

头影测量术对于阻塞性睡眠呼吸暂停综合征(OSAS)患者的解剖结构异常筛查很有用。

目的

全面评估患有或未患有腺样体扁桃体肥大的OSAS儿童的头影测量特征,并阐明头影测量变量与呼吸暂停低通气指数(AHI)严重程度之间的关系。

材料与方法

研究对象为39名4至12岁患有OSAS的儿童。对头骨结构进行了11项测量,包括它们之间的关系以及气道大小,以此来分析头影测量结果。此外,对腺样体和扁桃体肥大进行了分级。

结果

发现颅底角(BaSN和BaSPNS)与AHI评分升高相关(P<0.001)。上颌骨(SNA)和下颌骨(SNB)的突出度与AHI评分无关(P>0.05)。下颌平面长度(GnGo)和最小后气道间隙(MPAS)与AHI评分呈负相关(P<0.001)。MPAS与GnGo呈正相关(r=0.740,P<0.001),与下颌角(ArGoGn)呈负相关(r=-0.541,P<0.001)。关于BaSN、BaSPNS、ArGoGn、GnGoH、BaN-GnGo、MPAS、GnGO和MPH,头影测量数据与腺样体扁桃体肥大之间存在显著相关性(P<0.001)。

结论

OSAS儿童的头影测量数据与AHI评分严重程度之间存在显著相关性。腺样体扁桃体肥大对头影测量结果有不利影响。该研究明确要求对OSAS儿童的腺样体扁桃体肥大进行早期有效治疗。

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