由质粒介导的链霉素和壮观霉素耐药性。
Streptomycin and Spectinomycin resistance mediated by plasmids.
作者信息
Kawabe H, Tanaka T, Mitsuhashi S
出版信息
Antimicrob Agents Chemother. 1978 Jun;13(6):1031-5. doi: 10.1128/AAC.13.6.1031.
Abstract
Resistance to tetracycline (Tc), chloramphenicol (Cm), streptomycin (Sm), and sulfanilamide (Sa) was surveyed in clinical isolates of Escherichia coli and Shigella strains. Among the Sm Sa-resistant strains, the frequency of nonconjugative r (Sm Sa) plasmids was much higher than that of conjugative R plasmids encoding double resistance. The biochemical mechanism of Sm resistance mediated by the conjugative plasmids R(Tc Cm Sm Sa) and R(Cm Sm Sa) and about half the numbers of conjugative R(Tc Sm Sa) and R(Sm Sa) plasmids tested were found to be due to adenylylation of the drug. The remaining conjugative R(Tc Sm Sa) and R(Sm Sa) plasmids and all nonconjugative (Sm Sa) plasmids tested inactivated Sm by phosphorylation.
摘要
对大肠杆菌和志贺氏菌临床分离株的四环素（Tc）、氯霉素（Cm）、链霉素（Sm）和磺胺（Sa）耐药性进行了调查。在耐Sm Sa的菌株中，非接合性r（Sm Sa）质粒的频率远高于编码双重耐药性的接合性R质粒。发现由接合性质粒R（Tc Cm Sm Sa）和R（Cm Sm Sa）介导的Sm耐药性的生化机制以及大约一半经测试的接合性R（Tc Sm Sa）和R（Sm Sa）质粒是由于药物的腺苷酸化。其余经测试的接合性R（Tc Sm Sa）和R（Sm Sa）质粒以及所有非接合性（Sm Sa）质粒通过磷酸化使Sm失活。
相似文献
1
Streptomycin and Spectinomycin resistance mediated by plasmids.由质粒介导的链霉素和壮观霉素耐药性。
Antimicrob Agents Chemother. 1978 Jun;13(6):1031-5. doi: 10.1128/AAC.13.6.1031.
2
Nonconjugative plasmids encoding sulfanilamide resistance.编码磺胺耐药性的非接合质粒。
Antimicrob Agents Chemother. 1977 Sep;12(3):418-22. doi: 10.1128/AAC.12.3.418.
3
Drug resistance and distribution of R factors in Salmonella strains.沙门氏菌菌株中R因子的耐药性及分布
Antimicrob Agents Chemother. 1976 Jan;9(1):61-4. doi: 10.1128/AAC.9.1.61.
4
[Drug-resistance and its transferability of Shigella strains isolated in 1986 in Japan].
Kansenshogaku Zasshi. 1989 Jan;63(1):15-26. doi: 10.11150/kansenshogakuzasshi1970.63.15.
5
Episome-mediated transfer of drug resistance in Enterobacteriaceae. V. Spontaneous segregation and recombination of resistance factors in Salmonella typhimurium.肠杆菌科中耐药性的附加体介导转移。V. 鼠伤寒沙门氏菌中耐药因子的自发分离与重组。
J Bacteriol. 1962 Sep;84(3):422-30. doi: 10.1128/jb.84.3.422-430.1962.
6
R plasmids conferring multiple drug resistance from shigella isolated in Korea.从韩国分离出的具有多重耐药性的志贺氏菌R质粒。
J Hyg (Lond). 1984 Apr;92(2):153-60. doi: 10.1017/s0022172400064160.
7
[Group of derepressed pKMR plasmids found in wild strains of Shigella].[在志贺氏菌野生菌株中发现的去阻遏pKMR质粒组]
Antibiotiki. 1981 Sep;26(9):680-3.
8
Characterization and mobilization of nonconjugative plasmids encoding resistance to streptomycin and sulfanilamide.
Microbiol Immunol. 1987;31(11):1107-11. doi: 10.1111/j.1348-0421.1987.tb01342.x.
9
Drug resistance and conjugative R plasmids in fecal Escherichia coli strains isolated from healthy younger animals (chickens, piglets, calves) and children.从健康幼龄动物（鸡、仔猪、犊牛）和儿童分离出的粪便大肠杆菌菌株中的耐药性和接合性R质粒。
Microbiol Immunol. 1983;27(12):1031-41. doi: 10.1111/j.1348-0421.1983.tb02937.x.
10
Drug resistance and R plasmids in Escherichia coli strains isolated from broilers.从肉鸡中分离出的大肠杆菌菌株中的耐药性与R质粒
Microbiol Immunol. 1983;27(6):471-8. doi: 10.1111/j.1348-0421.1983.tb00606.x.
引用本文的文献
1
Inferring fitness landscapes and selection on phenotypic states from single-cell genealogical data.从单细胞谱系数据推断适应度景观及对表型状态的选择。
PLoS Genet. 2017 Mar 7;13(3):e1006653. doi: 10.1371/journal.pgen.1006653. eCollection 2017 Mar.
2
Ecological and genetic analysis of copper and streptomycin resistance in Pseudomonas syringae pv. syringae.丁香假单胞菌丁香致病变种中铜和链霉素抗性的生态学与遗传学分析
Appl Environ Microbiol. 1993 Apr;59(4):1018-24. doi: 10.1128/aem.59.4.1018-1024.1993.
3
Molecular nature of a streptomycin and sulfonamide resistance plasmid (pBP1) prevalent in clinical Escherichia coli strains and integration of an ampicillin resistance transposon (TnA).临床大肠杆菌菌株中普遍存在的链霉素和磺胺抗性质粒（pBP1）的分子特性以及氨苄青霉素抗性转座子（TnA）的整合
Antimicrob Agents Chemother. 1981 Mar;19(3):371-80. doi: 10.1128/AAC.19.3.371.
4
Dissemination of streptomycin and sulfonamide resistance by plasmid pBP1 in Escherichia coli.质粒pBP1在大肠杆菌中传播链霉素和磺胺抗性
Eur J Clin Microbiol. 1983 Oct;2(5):463-8. doi: 10.1007/BF02013905.
5
RSF1010 and a conjugative plasmid contain sulII, one of two known genes for plasmid-borne sulfonamide resistance dihydropteroate synthase.RSF1010和一种接合质粒含有sulII，它是已知的两个质粒介导的磺胺抗性二氢蝶酸合酶基因之一。
Antimicrob Agents Chemother. 1988 Nov;32(11):1684-92. doi: 10.1128/AAC.32.11.1684.
6
Plasmid-specified aminoglycoside-modifying enzymes in clinical isolates of Klebsiella pneumoniae.肺炎克雷伯菌临床分离株中的质粒编码氨基糖苷类修饰酶
Eur J Epidemiol. 1985 Mar;1(1):48-53. doi: 10.1007/BF00162312.
7
Nucleotide sequence of a spectinomycin adenyltransferase AAD(9) determinant from Staphylococcus aureus and its relationship to AAD(3") (9).来自金黄色葡萄球菌的壮观霉素腺苷转移酶AAD(9) 决定簇的核苷酸序列及其与AAD(3") (9) 的关系。
Mol Gen Genet. 1985;200(1):33-9. doi: 10.1007/BF00383309.
8
Genetic analyses of sulfonamide resistance and its dissemination in gram-negative bacteria illustrate new aspects of R plasmid evolution.对革兰氏阴性菌中磺胺耐药性及其传播的遗传分析揭示了R质粒进化的新方面。
Antimicrob Agents Chemother. 1991 Sep;35(9):1840-8. doi: 10.1128/AAC.35.9.1840.
本文引用的文献
1
Enzymatic Adenylylation of Streptomycin and Spectinomycin by R-Factor-Resistant Escherichia coli.R 因子抗性大肠杆菌对链霉素和壮观霉素的酶腺苷酰化作用。
Infect Immun. 1970 Jan;1(1):109-19. doi: 10.1128/iai.1.1.109-119.1970.
2
Mutants of Escherichia coli requiring methionine or vitamin B12.需要甲硫氨酸或维生素B12的大肠杆菌突变体。
J Bacteriol. 1950 Jul;60(1):17-28. doi: 10.1128/jb.60.1.17-28.1950.
3
Aminoglycoside antibiotics: inactivation by phosphorylation in Escherichia coli carrying R factors.氨基糖苷类抗生素：在携带R因子的大肠杆菌中通过磷酸化作用而失活
J Bacteriol. 1969 Nov;100(2):1144-6. doi: 10.1128/jb.100.2.1144-1146.1969.
4
Nonchromosomal antibiotic resistance in bacteria: genetic transformation of Escherichia coli by R-factor DNA.细菌中的非染色体抗生素抗性：R 因子 DNA 对大肠杆菌的遗传转化
Proc Natl Acad Sci U S A. 1972 Aug;69(8):2110-4. doi: 10.1073/pnas.69.8.2110.
5
Molecular structure of bacterial plasmids.细菌质粒的分子结构。
Bacteriol Rev. 1972 Sep;36(3):361-405. doi: 10.1128/br.36.3.361-405.1972.
6
R factor-mediated aminoglycoside antibiotic resistance in Pseudomonas aeruginosa: a new aminoglycoside 6'-N-acetyltransferase.R因子介导的铜绿假单胞菌对氨基糖苷类抗生素的耐药性：一种新的氨基糖苷6'-N-乙酰基转移酶
Antimicrob Agents Chemother. 1975 May;7(5):494-9. doi: 10.1128/AAC.7.5.494.
7
Nonconjugative plasmids encoding sulfanilamide resistance.编码磺胺耐药性的非接合质粒。
Antimicrob Agents Chemother. 1977 Sep;12(3):418-22. doi: 10.1128/AAC.12.3.418.
Zotero 插件