Aguilar-Salinas Carlos A, Rojas Rosalba, Gómez-Pérez Francisco J, Valles Victoria, Ríos-Torres Juan Manuel, Franco Aurora, Olaiz Gustavo, Rull Juan A, Sepúlveda Jaime
Departamento de Endocrinología y Metabolismo, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (INCMNSZ), Mexico City, Mexico.
Arch Med Res. 2004 Jan-Feb;35(1):76-81. doi: 10.1016/j.arcmed.2003.06.006.
Our objective was to describe the prevalence of the metabolic syndrome using World Health Organization (WHO) and National Cholesterol Education Program (NCEP-III) definitions in a population-based survey.
We performed an analysis of data from a Mexican nationwide, population-based study. The population was composed of 2,158 men and women aged 20-69 years sampled after a 9-12 h fasting period. Prevalence of the metabolic syndrome as defined by the NCEP-III definition and WHO criteria was estimated and case characteristics were assessed.
Age-adjusted prevalence was 13.61% for WHO criteria and 26.6% for the NCEP-III definition. Prevalence was 9.2 and 21.4%, respectively, in subjects without diabetes. Thirty five percent of affected cases were <40 years of age. In addition to criteria used for diagnosis, ca. 90% were either overweight or obese. In cases detected using WHO criteria, antihypertensive treatment or blood pressure reading >140/90 was found in 61.8%. The proportion of subjects who qualified for hypolipemiant treatment was lower: lifestyle modifications were needed in 42.1% and drug therapy was required in 18.9%. The same trends were found for cases detected using the NCEP definition.
Prevalence of the metabolic syndrome in Mexico is high. A large proportion of affected cases qualify for preventive actions for complications of the metabolic syndrome (i.e., weight loss, antihypertensive or hypolipemiant treatment). These results provide data for planning therapeutic programs for Mexican patients with the metabolic syndrome.
我们的目标是在一项基于人群的调查中，使用世界卫生组织（WHO）和美国国家胆固醇教育计划（NCEP-III）的定义来描述代谢综合征的患病率。
我们对一项墨西哥全国性的基于人群的研究数据进行了分析。研究对象为2158名年龄在20至69岁之间的男性和女性，均经过9至12小时禁食。估计了根据NCEP-III定义和WHO标准定义的代谢综合征患病率，并评估了病例特征。
根据WHO标准，年龄调整后的患病率为13.61%，根据NCEP-III定义为26.6%。在无糖尿病的受试者中，患病率分别为9.2%和21.4%。35%的受影响病例年龄小于40岁。除了用于诊断的标准外，约90%的病例超重或肥胖。在根据WHO标准检测出的病例中，61.8%的病例接受了抗高血压治疗或血压读数>140/90。符合降血脂治疗条件的受试者比例较低：42.1%的人需要进行生活方式改变，18.9%的人需要药物治疗。使用NCEP定义检测出的病例也发现了相同的趋势。
墨西哥代谢综合征的患病率很高。很大一部分受影响病例有资格采取预防代谢综合征并发症的措施（即减肥、抗高血压或降血脂治疗）。这些结果为规划针对墨西哥代谢综合征患者的治疗方案提供了数据。
