Tan B L L, Mustafa A M
Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Asia Pac J Public Health. 2003;15(2):118-23. doi: 10.1177/101053950301500208.
Bisphenol A is the monomer used in the manufacture of polycarbonate. Bisphenol A is also known to mimic the female hormone estrogen. In this study, the possibility of the leaching of bisphenol A from polycarbonate babies' bottles and feeding teats was investigated. Bisphenol A was extracted from water samples exposed to the bottles and teats using liquid-liquid extraction. Bisphenol A was analysed by gas chromatograph-mass spectrometer with quadrapole detector in selected ion monitoring mode. Mean leaching of bisphenol A from 100 used babies' bottles when filled with water at 25 degrees C and 80 degrees C were 0.71 +/- 1.65 ng/cm2 (mean +/- standard deviation) and 3.37 +/- 5.68 ng/cm2 respectively. Mean leaching of bisphenol A from 30 new babies' bottles when filled with water at 25 degrees C and 80 degrees C were 0.03 +/- 0.02 ng/cm2 and 0.18 degrees 0.30 ng/cm2 respectively. Bisphenol A was observed to have leached from babies' feeding teats into 37 degrees C water ranged from non-detectable to 22.86 ng/g. The technique employed in this study is fast, reliable and economical.
双酚A是用于制造聚碳酸酯的单体。已知双酚A会模拟女性荷尔蒙雌激素。在本研究中，对双酚A从聚碳酸酯婴儿奶瓶和奶嘴中浸出的可能性进行了调查。使用液液萃取法从接触奶瓶和奶嘴的水样中提取双酚A。采用气相色谱-质谱联用仪，在选择离子监测模式下，用四极杆检测器对双酚A进行分析。100个用过的婴儿奶瓶在25℃和80℃装满水时，双酚A的平均浸出量分别为0.71±1.65 ng/cm²（平均值±标准差）和3.37±5.68 ng/cm²。30个新的婴儿奶瓶在25℃和80℃装满水时，双酚A的平均浸出量分别为0.03±0.02 ng/cm²和0.18±0.30 ng/cm²。观察到双酚A从婴儿奶嘴浸出到37℃水中的量在未检出到22.86 ng/g之间。本研究采用的技术快速、可靠且经济。
