Otake Takamitsu, Yoshinaga Jun, Yanagisawa Yukio
Institute of Environmental Studies, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo 113-8656, Japan.
J Expo Anal Environ Epidemiol. 2004 Nov;14(7):524-8. doi: 10.1038/sj.jea.7500352.
Phthalate esters and phosphate esters in samples of indoor air from 27 houses in the Tokyo Metropolitan area were quantified using gas chromatograph/mass spectrometer and gas chromatograph/flame photometric detector after adsorption on to charcoal and solvent extraction. The median concentrations of diethyl phthalate, dibutyl phthalate (DBP), butylbenzyl phthalate, dicyclohexyl phthalate and diethylhexyl phthalate were 0.10, 0.39, 0.01, 0.07 and 0.11 microg/m(3), respectively. The median concentrations of tributyl phosphate, tris(2-chloroethyl) phosphate, triphenyl phosphate and tris(2-butoxyethyl) phosphate were less than 0.001 microg/m(3). DBP was detected at the highest concentration (6.18 microg/m(3)) in a new residential housing. This research indicated that exposure to phthalate esters through inhalation of air from the indoor environment is as important as dietary intake of phthalate esters, and can contribute to daily intake to a much greater extent than has been assumed hitherto.
采用气相色谱/质谱联用仪和气相色谱/火焰光度检测器，通过活性炭吸附和溶剂萃取，对东京都市区27所房屋室内空气样本中的邻苯二甲酸酯和磷酸酯进行了定量分析。邻苯二甲酸二乙酯、邻苯二甲酸二丁酯（DBP）、邻苯二甲酸丁苄酯、邻苯二甲酸二环己酯和邻苯二甲酸二（2-乙基己基）酯的中位浓度分别为0.10、0.39、0.01、0.07和0.11微克/立方米。磷酸三丁酯、磷酸三（2-氯乙基）酯、磷酸三苯酯和磷酸三（2-丁氧基乙基）酯的中位浓度低于0.001微克/立方米。在一套新建住宅中检测到DBP的浓度最高（6.18微克/立方米）。该研究表明，通过吸入室内环境空气接触邻苯二甲酸酯与通过饮食摄入邻苯二甲酸酯同样重要，并且对每日摄入量的贡献程度比迄今所认为的要大得多。
