Zimmerberg Joshua, McLaughlin Stuart
Laboratory of Cellular and Molecular Biophysics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.
Curr Biol. 2004 Mar 23;14(6):R250-2. doi: 10.1016/j.cub.2004.02.060.
An important new structure suggests the BAR domain is a membrane-binding module that can both produce and sense membrane curvature. BAR resembles a banana that binds membranes electrostatically through its positively charged, concave surface.
一种重要的新结构表明,BAR结构域是一种膜结合模块,既能产生又能感知膜曲率。BAR类似于一根香蕉,通过其带正电的凹面与膜静电结合。