Gage Andrew A, Baust John G
School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 14214, USA.
Technol Cancer Res Treat. 2004 Apr;3(2):187-99. doi: 10.1177/153303460400300212.
Cryosurgery, a method of treating disease by the production of freezing temperatures in the tissue, is a useful technique for the treatment of tumors. When the modern era of cryosurgery began in the mid 1960's, the technique was used only for tumors easily accessible by direct observation or via endoscopy, such as those of the skin, oral cavity, and prostate gland. In general, the technique had limited usefulness in the next two decades. However, with the advent of intraoperative ultrasound as a method of monitoring the process of freezing and with the development of more effective cryosurgical apparatus, the cryosurgical treatment of tumors of the viscera and other deep tissues became practical in the 1990's. This review assesses the present day status of cryosurgery in the management of diverse tumors.
冷冻手术是一种通过在组织中产生低温来治疗疾病的方法，是治疗肿瘤的一种有用技术。当冷冻手术的现代时代始于20世纪60年代中期时，该技术仅用于通过直接观察或内窥镜检查易于触及的肿瘤，如皮肤、口腔和前列腺的肿瘤。一般来说，在接下来的二十年里，该技术的用途有限。然而，随着术中超声作为一种监测冷冻过程的方法的出现以及更有效的冷冻手术设备的发展，内脏和其他深部组织肿瘤的冷冻手术治疗在20世纪90年代变得切实可行。本综述评估了冷冻手术在各种肿瘤管理中的现状。
