Walian Peter, Cross Timothy A, Jap Bing K
Life Sciences Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, CA 94720, USA.
Genome Biol. 2004;5(4):215. doi: 10.1186/gb-2004-5-4-215. Epub 2004 Mar 15.
Improvements in the fields of membrane-protein molecular biology and biochemistry, technical advances in structural data collection and processing, and the availability of numerous sequenced genomes have paved the way for membrane-protein structural genomics efforts. There has been significant recent progress, but various issues essential for high-throughput membrane-protein structure determination remain to be resolved.
膜蛋白分子生物学和生物化学领域的进展、结构数据收集与处理方面的技术进步以及众多已测序基因组的可得性，为膜蛋白结构基因组学的研究铺平了道路。最近已经取得了重大进展，但高通量膜蛋白结构测定所必需的各种问题仍有待解决。
