Dodia Sumita, Bajpai Ritu, Singh B Geetha
Department of Botany, St. John's College, Agra 282 002, India.
Hindustan Antibiot Bull. 2002 Feb-Nov;44(1-4):47-8.
The in vitro activity of griseofulvin and ketoconazole was investigated against Trichophyton mentagrophytes (Robin) Blanchard and T. Simii (Pinoy) Stockdale, Mackenzie and Austwick. A gradual decrease in growth was observed with increase in concentration of both antibiotics. Ketoconazole was the more effective antibiotic than griseofulvin as it observed to inhibit > 50% mycelial weight even at a lower concentration of 100 ppm. While griseofulvin was effective to cause > 50% growth inhibition only at higher dosage of 400 ppm.
研究了灰黄霉素和酮康唑对须癣毛癣菌（Robin）Blanchard以及石膏样毛癣菌（Pinoy）Stockdale、Mackenzie和Austwick的体外活性。随着两种抗生素浓度的增加，观察到生长逐渐减少。酮康唑是比灰黄霉素更有效的抗生素，因为即使在100 ppm的较低浓度下，也观察到它能抑制> 50%的菌丝体重量。而灰黄霉素仅在400 ppm的较高剂量下才有效导致> 50%的生长抑制。
