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对基层医疗中抑郁症患者精神运动迟缓的客观评估。

Objective assessment of psychomotor retardation in primary care patients with depression.

作者信息

Iverson Grant L

机构信息

Department of Psychiatry, University of British Columbia & HeartLink Canada, Inc., Vancouver, Canada.

出版信息

J Behav Med. 2004 Feb;27(1):31-7. doi: 10.1023/b:jobm.0000013642.43978.f9.

DOI:10.1023/b:jobm.0000013642.43978.f9
PMID:15065474
Abstract

The relationship between activity level and depression in primary care outpatients was examined. Forty-eight patients with depression and 25 general medical controls wore a heart and activity level monitor for 24 h. Minute-averaged horizontal movement was collected. Patients with depression were sorted into two equal groups based on a median split of their Beck Depression Inventory-II scores. ANOVAs revealed significant main effects for average movement over the 24-h interval, average movement between 12 and 6 P.M., and a measure of "high activity" level. Patients with more severe depression had lower activity levels than the other two patient groups. The nondepressed and less severely depressed groups were combined and compared to the more severely depressed group using a standard discriminant function analysis. The overall correct classification rate was 74.0%, with 86% of the combined group and 50% of the more severely depressed group correctly classified. Patients with low activity levels were 6.0 times more likely to fall in the severely depressed group than patients with more normal activity levels.

摘要

研究了基层医疗门诊患者的活动水平与抑郁之间的关系。48名抑郁症患者和25名普通内科对照者佩戴心脏和活动水平监测器24小时。收集每分钟平均水平运动数据。根据贝克抑郁量表-II得分的中位数划分,将抑郁症患者分为两组。方差分析显示,在24小时时间段内的平均运动、下午12点至6点之间的平均运动以及“高活动”水平指标存在显著的主效应。重度抑郁症患者的活动水平低于其他两组患者。将非抑郁症组和轻度抑郁症组合并,并使用标准判别函数分析与重度抑郁症组进行比较。总体正确分类率为74.0%,合并组的正确分类率为86%,重度抑郁症组的正确分类率为50%。活动水平低的患者属于重度抑郁症组的可能性是活动水平正常的患者的6.0倍。

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引用本文的文献

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Psychomotor retardation in depression: a systematic review of diagnostic, pathophysiologic, and therapeutic implications.抑郁症的精神运动阻滞:诊断、病理生理和治疗意义的系统综述。
Biomed Res Int. 2013;2013:158746. doi: 10.1155/2013/158746. Epub 2013 Oct 30.
2
Psychomotor retardation in depression: biological underpinnings, measurement, and treatment.抑郁症中的精神运动阻滞:生物学基础、测量和治疗。
Prog Neuropsychopharmacol Biol Psychiatry. 2011 Mar 30;35(2):395-409. doi: 10.1016/j.pnpbp.2010.10.019. Epub 2010 Oct 31.

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