Aronen E T, Teicher M H, Geenens D, Curtin S, Glod C A, Pahlavan K
Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
J Am Acad Child Adolesc Psychiatry. 1996 Jun;35(6):752-63. doi: 10.1097/00004583-199606000-00015.
To determine whether there is an association between activity levels and the severity and nature of depressive symptoms.
Locomotor activity was quantified in 27 consecutively selected hospitalized prepubertal children. Activity was measured in 5-minute epochs over a period of 72 hours using belt-worn monitors. Depressive symptoms were rated using the Children's Depression Rating Scale-Revised, the Children's Depression Inventory, and an observer rating scale for nursing staff.
Measures of reduced daytime activity correlated with scores on the Children's Depression Rating Scale and the observer rating scale, but not the Children's Depression Inventory. Stepwise regression indicated that the strongest association occurred between a composite measure of severity, age, and percentage of low-level diurnal activity periods (r = .724, p < .0005). Activity measures correlated with clinical ratings of sadness, low self-esteem, anhedonia, and physical complaints, and to a lesser degree with ratings of hypoactivity, fatigue, and slow speech.
Reduced levels of activity correlated significantly with clinical ratings of depressive severity across diagnostic groups. The development of objective measures of depressive severity may have prognostic and therapeutic implications.
确定活动水平与抑郁症状的严重程度及性质之间是否存在关联。
对连续入选的27名青春期前住院儿童的运动活动进行量化。使用佩戴在腰部的监测仪，在72小时内以5分钟为一个时间段测量活动情况。使用儿童抑郁评定量表修订版、儿童抑郁量表以及护理人员的观察评定量表对抑郁症状进行评分。
白天活动减少的测量结果与儿童抑郁评定量表及观察评定量表的得分相关，但与儿童抑郁量表无关。逐步回归分析表明，严重程度综合测量、年龄与低水平日间活动时间段百分比之间的关联最为显著（r = .724，p < .0005）。活动测量结果与悲伤、自卑、快感缺失及身体不适的临床评分相关，与活动减退、疲劳及语速缓慢的评分相关性较小。
活动水平降低与各诊断组抑郁严重程度的临床评分显著相关。抑郁严重程度客观测量方法的发展可能具有预后和治疗意义。
