Katz Patricia P, Yelin Edward H, Eisner Mark D, Earnest Gillian, Blanc Paul D
Department of Medicine, University of California-San Francisco, 350 Parnassus Ave., Suite 609, San Francisco, CA 94143-0924, USA.
J Clin Epidemiol. 2004 Mar;57(3):259-67. doi: 10.1016/j.jclinepi.2003.08.007.
We examined the prevalence of disability in valued life activities (VLAs) among a group of adults with asthma and the impact of general physical function and performance of VLAs on asthma-specific quality of life (QOL).
Interview data collected from two waves of a longitudinal cohort study were used to examine the prevalence of disability in VLAs, the cross-sectional association of general function and performance of VLAs with QOL, and the longitudinal association of changes in general function and changes in performance of VLAs with changes in QOL. General function was assessed with the SF-12; VLAs were assessed with a newly developed measure.
A substantial portion of subjects reported disability in VLAs. VLA function was a stronger predictor of QOL than general physical function in cross-sectional and longitudinal analyses.
Performance of VLAs is more closely tied to asthma-specific QOL than is general physical function.
我们研究了一组哮喘成年患者在有价值生活活动（VLA）中的残疾发生率，以及一般身体功能和VLA表现对哮喘特异性生活质量（QOL）的影响。
从一项纵向队列研究的两波访谈数据中，用于检查VLA中的残疾发生率、VLA的一般功能和表现与QOL的横断面关联，以及一般功能变化和VLA表现变化与QOL变化的纵向关联。一般功能用SF - 12评估；VLA用一种新开发的测量方法评估。
相当一部分受试者报告在VLA中有残疾。在横断面和纵向分析中，VLA功能比一般身体功能更能预测QOL。
与一般身体功能相比，VLA表现与哮喘特异性QOL的联系更为紧密。
