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一名慢性肉芽肿病患者中与致命菌血症相关的菲氏弗朗西斯菌鉴定问题。

Problems in identification of Francisella philomiragia associated with fatal bacteremia in a patient with chronic granulomatous disease.

作者信息

Friis-Møller A, Lemming L E, Valerius N H, Bruun B

机构信息

Department of Clinical Microbiology, Hvidovre Hospital, Denmark.

出版信息

J Clin Microbiol. 2004 Apr;42(4):1840-2. doi: 10.1128/JCM.42.4.1840-1842.2004.

Abstract

Francisella philomiragia is a rare gram-negative, halophilic coccobacillus with bizarre spherical forms on primary isolation. A case of F. philomiragia bacteremia in a 24-year-old patient with chronic granulomatous disease is reported. Identification of F. philomiragia was problematic with conventional tests but was done correctly and rapidly by kit 16S ribosomal DNA sequencing.

摘要

嗜肺弗朗西斯菌是一种罕见的革兰氏阴性嗜盐球杆菌,初次分离时呈奇异的球形。本文报道了一例24岁慢性肉芽肿病患者发生嗜肺弗朗西斯菌菌血症的病例。用传统检测方法鉴定嗜肺弗朗西斯菌存在问题,但通过试剂盒16S核糖体DNA测序能够正确且快速地完成鉴定。

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本文引用的文献

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Chronic granulomatous disease.慢性肉芽肿病
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Pediatr Infect Dis J. 1997 Apr;16(4):420-2. doi: 10.1097/00006454-199704000-00021.

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