Gallego-Huidobro J, Pastor L M, Calvo A
Department of Cellular Biology, School of Medicine, University of Murcia, Spain.
J Morphol. 1992 Jun;212(3):191-200. doi: 10.1002/jmor.1052120302.
Study of the esophageal microscopic morphology of adult Rana perezi by light and electron microscopy discloses some large folds throughout the esophagus that are in themselves ringed. Glandular ostia open in the furrows of the luminal surface. The esophageal wall is made up of a connective adventitia rich in melanocytes, a muscular tunica, a connective and glandular subepithelial layer, and a pseudostratified ciliated epithelium. This epithelium basically consists of ciliated, goblet, basal, microvillous-apex, and migratory cells. Two types of goblet cells are distinguished with regard to the granular ultrastructure. The microvillous-apex cell has not been found in other amphibians. It shows a very differentiated morphology with a high number of mitochondria. The basal cells give the epithelium a pseudostratified morphology, and they have a proliferative function. Glands are branched and drain through an excretory duct that has a monolayered mucosecreting epithelium. The glandular units are formed by two principal types of cells: mucosecretory and serous.
通过光学显微镜和电子显微镜对成年泽蛙食管微观形态的研究发现，整个食管有一些大的褶皱，这些褶皱本身呈环状。腺孔开口于管腔表面的沟内。食管壁由富含黑素细胞的结缔组织外膜、肌层、结缔组织和腺性上皮下层以及假复层纤毛上皮组成。这种上皮主要由纤毛细胞、杯状细胞、基底细胞、微绒毛顶端细胞和游走细胞组成。根据颗粒超微结构区分出两种类型的杯状细胞。微绒毛顶端细胞在其他两栖动物中尚未发现。它表现出非常分化的形态，线粒体数量很多。基底细胞使上皮呈现假复层形态，并且它们具有增殖功能。腺体为分支状，通过具有单层分泌黏液上皮的排泄管排出。腺单位由两种主要类型的细胞组成：分泌黏液的细胞和浆液性细胞。
