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年龄、合并症及生活方式因素对勃起功能的影响:坦佩雷老年男性泌尿学研究(TAMUS)

Effects of age, comorbidity and lifestyle factors on erectile function: Tampere Ageing Male Urological Study (TAMUS).

作者信息

Shiri Rahman, Koskimäki Juha, Häkkinen Jukka, Tammela Teuvo L J, Huhtala Heini, Hakama Matti, Auvinen Anssi

机构信息

Tampere School of Public Health, Fin-33014 University of Tampere, Tampere, Finland.

出版信息

Eur Urol. 2004 May;45(5):628-33. doi: 10.1016/j.eururo.2003.11.020.

DOI:10.1016/j.eururo.2003.11.020
PMID:15082206
Abstract

OBJECTIVES

We estimated the effects of sociodemographic, medical and lifestyle factors on erectile function in a population-based sample of 50- to 75-year-old Finnish men.

METHODS

The target population consisted of all non-institutionalized men aged 50, 60 or 70 years residing in the study area in 1994. The questionnaire was mailed to 3143 men in 1994 and 2198 (70%) responded. A repeat survey was carried out in 1999 with questionnaires mailed to 2864 men in the baseline sample, who were still alive, and 2133 (75%) responded. Erectile function was assessed by two questions on the subject's ability to achieve and maintain an erection sufficient for intercourse and function was classified into none, minimal, moderate or complete erectile dysfunction (ED) for analysis with scores 0-3 respectively.

RESULTS

The mean ED score increased markedly with age. It increased from 0.82 for men aged 50 years to 1.85 for those aged 75. After controlling for the effects of sociodemographic, medical and lifestyle factors, the mean ED score increased by 1.1% (95%CI 1.0-1.3) per year of age. Mean ED score increased most slowly between the ages of 50 and 55 years (regression coefficients (r)=0.02 or 0.6% for one year increments, p=0.89) and most rapidly between 60 and 70 years (r=0.06 or 1.8%, p<0.001). In addition to age, diabetes (r=17.5%), heart disease (r=6.5%), hypertension (r=5.1%), cerebrovascular disease (5.8%) and smoking (4.6%) were associated with an increased risk of ED.

CONCLUSIONS

Erectile dysfunction increases markedly with age, especially after the age of 60 years. Smokers and men with diabetes, heart disease, hypertension, and cerebrovascular disease are at increased risk.

摘要

目的

我们在一个基于人群的50至75岁芬兰男性样本中,评估了社会人口统计学、医学和生活方式因素对勃起功能的影响。

方法

目标人群包括1994年居住在研究区域的所有50岁、60岁或70岁的非机构化男性。1994年向3143名男性邮寄了问卷,2198人(70%)做出了回应。1999年进行了重复调查,向基线样本中仍在世的2864名男性邮寄了问卷,2133人(75%)做出了回应。通过两个关于受试者实现和维持足以进行性交的勃起能力的问题来评估勃起功能,并将功能分为无、轻度、中度或完全勃起功能障碍(ED),分别用0至3分进行分析。

结果

勃起功能障碍平均得分随年龄显著增加。从50岁男性的0.82分增加到75岁男性的1.85分。在控制了社会人口统计学、医学和生活方式因素的影响后,勃起功能障碍平均得分每年增加1.1%(95%可信区间1.0 - 1.3)。勃起功能障碍平均得分在50至55岁之间增加最慢(回归系数(r)=0.02或每年增加0.6%,p = 0.89),在60至70岁之间增加最快(r = 0.06或1.8%,p < 0.001)。除年龄外,糖尿病(r = 17.5%)、心脏病(r = 6.5%)、高血压(r = 5.1%)、脑血管疾病(5.8%)和吸烟(4.6%)与勃起功能障碍风险增加相关。

结论

勃起功能障碍随年龄显著增加,尤其是60岁以后。吸烟者以及患有糖尿病、心脏病、高血压和脑血管疾病的男性风险增加。

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