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我的肺功能真的那么好吗?流速型肺活量计存在导致测试结果升高的问题。

Is my lung function really that good? Flow-type spirometer problems that elevate test results.

作者信息

Townsend Mary C, Hankinson John L, Lindesmith Larry A, Slivka William A, Stiver Gregg, Ayres Gerald T

机构信息

M.C. Townsend Associates, Pittsburgh, PA 15228-1824, USA.

出版信息

Chest. 2004 May;125(5):1902-9. doi: 10.1378/chest.125.5.1902.

Abstract

Most spirometry errors reduce test results, and it is widely assumed that measurement accuracy is guaranteed by frequent spirometer calibrations or calibration checks. However, zero errors and changes in flow-type spirometer sensors may occur during testing that significantly elevate test results, even though the spirometer was calibrated recently. To draw attention to these often-unrecognized problems, this report presents anomalous spirograms and test results obtained from occupational medicine clinics and hospital pulmonary function laboratories during quality assurance spirogram reviews. The spurious results appear to have been caused by inaccurate zeroing of the flow sensor, or by condensation, mucus deposition, or unstable calibration of various flow-type spirometers. These errors elevated some FVCs to 144 to 204% of predicted and probably caused 40% of 121 middle-aged working men in respirator medical clearance programs to record both FVC and FEV1 > 120% of predicted. Since spirometers report the largest values from a test, these errors must be recognized and deleted to avoid false-negative interpretations. Flow-type spirometer users at all levels, from the technician to the interpreter of test results, should be aware of the potential for and the appearance of these errors in spirograms.

摘要

大多数肺量计误差会降低测试结果,人们普遍认为通过频繁校准或检查校准肺量计可确保测量准确性。然而,在测试过程中,流量型肺量计传感器可能会出现零点误差和变化,这会显著提高测试结果,即使肺量计最近已经校准过。为了引起人们对这些常常未被认识到的问题的关注,本报告展示了在质量保证肺量图审查期间从职业医学诊所和医院肺功能实验室获得的异常肺量图和测试结果。这些虚假结果似乎是由流量传感器调零不准确、冷凝、黏液沉积或各种流量型肺量计校准不稳定造成的。这些误差将一些用力肺活量(FVC)提高到预测值的144%至204%,可能导致在呼吸器医学检查项目中的121名中年在职男性中有40%的人记录的FVC和第1秒用力呼气容积(FEV1)均大于预测值的120%。由于肺量计报告的是测试中的最大值,必须识别并消除这些误差,以避免假阴性解读。从技术人员到测试结果解读人员,各级流量型肺量计使用者都应意识到肺量图中这些误差的可能性及表现形式。

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