Dirksen A, Madsen F, Pedersen O F, Vedel A M, Kok-Jensen A
Department of Pulmonary Medicine, Bispebjerg Hospital, Copenhagen, Denmark.
Thorax. 1996 Oct;51(10):973-6. doi: 10.1136/thx.51.10.973.
A study was undertaken to test the long term performance of a small hand held spirometer for self-administered serial spirometric testing.
Thirty turbine pocket spirometers (MicroMedical DiaryCard) were used in a clinical trial on 22 emphysematous patients with severe alpha 1-antitrypsin deficiency. The spirometers were able to store the date, time, forced expiratory volume in one second (FEV1), forced vital capacity (FVC), peak expiratory flow (PEF), and flow-volume loop for each blow. Every four weeks when the patients came for alpha 1-antitrypsin infusions the performance of their spirometer was checked before and after retrieval of the data from the spirometer. Calibration checks were threefold and included volume calibration with a 1.0 litre and 3.0 litre syringe, and flow calibration with a decompression calibrator.
After two years of study the mean number of spirometric recordings performed per spirometer was 693 (range 237-1178), and the mean number of calibration checks was 33 (range 2-57). The coefficient of variation of the calibration signal was 1-2% for syringes and 0.5-1% for the decompression calibrator. The bearings of one turbine exhibited excessive friction after 17 months. None of the other 29 instruments showed drift, and a general drift of all spirometers towards larger or smaller readings could not be shown. However, unforeseen problems in the stability of the calibrating devices were observed.
The small hand held turbine spirometers are suitable for long term patient-administered serial spirometric testing. The two year durability is acceptable and the long term reproducibility excellent.
开展了一项研究，以测试一种小型手持式肺活量计用于自我管理的系列肺活量测定的长期性能。
在一项针对22例患有严重α1抗胰蛋白酶缺乏症的肺气肿患者的临床试验中，使用了30台涡轮袖珍肺活量计（MicroMedical DiaryCard）。这些肺活量计能够存储每次吹气的日期、时间、一秒用力呼气量（FEV1）、用力肺活量（FVC）、呼气峰值流量（PEF）和流量-容积环。每四周，当患者前来接受α1抗胰蛋白酶输注时，在从肺活量计检索数据之前和之后检查其肺活量计的性能。校准检查包括三个方面，即用1.0升和3.0升注射器进行容积校准，以及用减压校准器进行流量校准。
经过两年的研究，每台肺活量计的平均肺活量测定记录次数为693次（范围为237 - 1178次），平均校准检查次数为33次（范围为2 - 57次）。注射器校准信号的变异系数为1 - 2%，减压校准器的变异系数为0.5 - 1%。17个月后，一台涡轮的轴承出现过度摩擦。其他29台仪器均未显示漂移，且未发现所有肺活量计向更大或更小读数的总体漂移情况。然而，观察到校准设备稳定性方面存在一些意外问题。
小型手持式涡轮肺活量计适用于患者长期自我管理的系列肺活量测定。两年的耐用性是可以接受的，长期再现性极佳。
