希腊雅典铜绿假单胞菌产超广谱β-内酰胺酶SHV-5菌株的医院感染暴发
Nosocomial outbreak of extended-spectrum beta-lactamase SHV-5-producing isolates of Pseudomonas aeruginosa in Athens, Greece.
作者信息
Poirel Laurent, Lebessi Evangelia, Castro Marisa, Fèvre Cindy, Foustoukou Maria, Nordmann Patrice
机构信息
Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris Sud, 78 rue du Général Leclerc, 94275 Le Kremlin-Bicêtre cedex, France.
出版信息
Antimicrob Agents Chemother. 2004 Jun;48(6):2277-9. doi: 10.1128/AAC.48.6.2277-2279.2004.
Abstract
Seven nonrepetitive Pseudomonas aeruginosa isolates producing the clavulanic acid-inhibited extended-spectrum beta-lactamase SHV-5 were isolated in the same hospital in Athens, Greece, from 1998 to 2002. All isolates except one were clonally related, and the bla(SHV-5) gene was chromosomally located. This study underlined that this gene, which is widespread in Enterobacteriaceae in Greece, may disseminate also in P. aeruginosa.
摘要
1998年至2002年期间，在希腊雅典的同一家医院分离出7株产生克拉维酸抑制的超广谱β-内酰胺酶SHV-5的非重复性铜绿假单胞菌菌株。除一株外，所有分离株均为克隆相关，bla(SHV-5)基因位于染色体上。这项研究强调，该基因在希腊的肠杆菌科中广泛存在，也可能在铜绿假单胞菌中传播。
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