人参提取物及ArginMax（一种用于增强女性性功能的营养补充剂）的雌激素生物活性测定。
Estrogen bioassay of ginseng extract and ArginMax, a nutritional supplement for the enhancement of female sexual function.
作者信息
Polan Mary Lake, Hochberg Richard B, Trant Aileen S, Wuh Hank C K
机构信息
Department of Gynecology/Obstetrics, Stanford University School of Medicine, Stanford, California, USA.
出版信息
J Womens Health (Larchmt). 2004 May;13(4):427-30. doi: 10.1089/154099904323087114.
PURPOSE
To determine whether ArginMax (The Daily Wellness Co., Sunnyvale, CA) or the Panax ginseng extract it contains has any estrogenic activity. ArginMax for Women, a nutritional supplement for optimization of sexual health, contains L-arginine, ginseng, ginkgo, damiana, multivitamins, and minerals.
METHODS
A human endometrial adenocarcinoma cell line, Ishikawa, which contains an alkaline phosphatase (AP) enzyme sensitive to estrogen stimulation, was used in a bioassay to determine whether Panax ginseng or ArginMax contained estrogenic components.
RESULTS
Neither ArginMax nor Panax ginseng stimulated AP at any of the concentrations tested.
CONCLUSIONS
No estrogenic activity was evident in the sample of Panax ginseng extract tested or in a sample of ArginMax containing this extract in combination with other ingredients.
目的
确定精氨酸能量素（加利福尼亚州森尼韦尔市每日健康公司生产）或其所含的人参提取物是否具有任何雌激素活性。女性用精氨酸能量素是一种用于优化性健康的营养补充剂，含有L - 精氨酸、人参、银杏、达米阿那、多种维生素和矿物质。
方法
使用一种人子宫内膜腺癌细胞系——石川细胞系，该细胞系含有一种对雌激素刺激敏感的碱性磷酸酶（AP），通过生物测定来确定人参或精氨酸能量素是否含有雌激素成分。
结果
在任何测试浓度下，精氨酸能量素和人参均未刺激碱性磷酸酶。
结论
在所测试的人参提取物样品或含有该提取物及其他成分的精氨酸能量素样品中，均未发现明显的雌激素活性。
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