Johnston Elizabeth, Johnson Shanthi, McLeod Peter, Johnston Mark
School of Nutrition and Dietetics, Acadia University, Wolfville, NS B4P 2R6.
Can J Public Health. 2004 May-Jun;95(3):179-83. doi: 10.1007/BF03403643.
Data from the 1995 Nova Scotia Health Survey were analyzed to determine the relation between body mass index (BMI) and the risk of depression as measured by the Center for Epidemiological Studies Depression Scale (CES-D).
Clinical measures for height and weight and CES-D scores were available for 2,482 subjects from an initial sample of 5,578 Nova Scotians stratified probabilistically to be representative of age, gender and area of residence. BMIs were categorized according to the international standards (BMI 18.5-24.9 acceptable weight; 25-29.9 overweight; > or = 30 obese).
More men than women were classified as overweight (43.2% vs. 28.3%) but slightly more women than men were obese (25.6% vs. 23.4%). Based on the summary score of the CES-D, 14.2% were categorized as at risk for depression (> or = 16). Logistic regression indicated that lower education (p < 0.001) and income (p < 0.001), and BMI category (p < 0.05) were all significantly related to an increased risk of depression. The odds ratio for the association between obesity and depression, after controlling for education and income, was 1.41 [95% CI = 1.07-1.86].
More studies are needed to ascertain the mechanism by which obesity and depression could be related and the significance of this relation for the prevention and treatment of both obesity and depression. Given the effects of depression, we suggest that health professionals should assess their obese patients for risk of depression before embarking on a weight management protocol.
分析1995年新斯科舍省健康调查的数据,以确定体重指数(BMI)与通过流行病学研究中心抑郁量表(CES-D)测量的抑郁风险之间的关系。
从5578名新斯科舍人的初始样本中选取了2482名受试者,这些受试者按年龄、性别和居住地区进行概率分层,可获得身高、体重的临床测量数据和CES-D评分。BMI根据国际标准进行分类(BMI 18.5 - 24.9为正常体重;25 - 29.9为超重;≥30为肥胖)。
被归类为超重的男性多于女性(43.2%对28.3%),但肥胖的女性略多于男性(25.6%对23.4%)。根据CES-D的总分,14.2%被归类为有抑郁风险(≥16)。逻辑回归表明,较低的教育程度(p < 0.001)、收入(p < 0.001)和BMI类别(p < 0.05)均与抑郁风险增加显著相关。在控制教育程度和收入后,肥胖与抑郁之间关联的优势比为1.41 [95%可信区间 = 1.07 - 1.86]。
需要更多研究来确定肥胖与抑郁之间可能存在关联的机制,以及这种关联对肥胖和抑郁的预防与治疗的意义。鉴于抑郁的影响,我们建议健康专业人员在开始体重管理方案之前,应对肥胖患者进行抑郁风险评估。