Department of Epidemiology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
J Womens Health (Larchmt). 2009 Oct;18(10):1687-92. doi: 10.1089/jwh.2008.1175.
To determine the age and sex variations in the associations between obesity and depression.
This analysis was based on data from 59,652 adults >or=18 years of age in the provinces of Nova Scotia, Quebec, Saskatchewan, Alberta, and British Columbia, who participated in the Canadian Community Health Survey conducted in 2005. The survey included a set of 27 questions about symptoms of depression, which were taken from the Composite International Diagnostic Interview. Based on these questions, depression scores were calculated and used to define depression, which corresponds to a 90% likelihood of a positive diagnosis of major depressive episode. Body weight and height were based on self-report.
The prevalence of depression was 5.3% in adults living in the five provinces and was higher in women than in men. People with abnormal body weight tended to have an increased risk of depression. On average, obesity and being underweight were associated with approximately 30% and 40% increases in depression, respectively. Particularly in women, depression was more markedly associated with obesity in the 18-39 year age group (OR 1.67, 95% CI 1.29-2.15) and with being underweight in the 40-59 year age group (OR 2.23, 95% CI 1.45-3.42) than other age groups.
Obesity is associated with an increased risk of depression in younger women.
确定肥胖与抑郁之间关联的年龄和性别变化。
本分析基于 2005 年参加加拿大社区健康调查的新斯科舍省、魁北克省、萨斯喀彻温省、艾伯塔省和不列颠哥伦比亚省 59652 名年龄≥18 岁的成年人的数据。该调查包括一组 27 个关于抑郁症状的问题，这些问题来自综合国际诊断访谈。根据这些问题，计算了抑郁评分并用于定义抑郁，这对应于主要抑郁发作阳性诊断的 90%可能性。体重和身高基于自我报告。
在这五个省份生活的成年人中，抑郁的患病率为 5.3%，女性高于男性。体重异常的人往往有更高的抑郁风险。平均而言，肥胖和体重不足分别与抑郁风险增加约 30%和 40%相关。特别是在女性中，肥胖与 18-39 岁年龄组的抑郁（OR 1.67，95%CI 1.29-2.15）和 40-59 岁年龄组的体重不足（OR 2.23，95%CI 1.45-3.42）的相关性比其他年龄组更显著。
肥胖与年轻女性抑郁风险增加有关。
