Reynolds Kenneth J, Vernon Suzanne D, Bouchery Ellen, Reeves William C
Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, U,S,A.
Cost Eff Resour Alloc. 2004 Jun 21;2(1):4. doi: 10.1186/1478-7547-2-4.
Chronic fatigue syndrome (CFS) is a chronic incapacitating illness that affects between 400,000 and 800,000 Americans. Despite the disabling nature of this illness, scant research has addressed the economic impact of CFS either on those affected or on the national economy. METHODS: We used microsimulation methods to analyze data from a surveillance study of CFS in Wichita, Kansas, and derive estimates of productivity losses due to CFS. RESULTS: We estimated a 37% decline in household productivity and a 54% reduction in labor force productivity among people with CFS. The annual total value of lost productivity in the United States was $9.1 billion, which represents about $20,000 per person with CFS or approximately one-half of the household and labor force productivity of the average person with this syndrome. CONCLUSION: Lost productivity due to CFS was substantial both on an individual basis and relative to national estimates for other major illnesses. CFS resulted in a national productivity loss comparable to such losses from diseases of the digestive, immune and nervous systems, and from skin disorders. The extent of the burden indicates that continued research to determine the cause and potential therapies for CFS could provide substantial benefit both for individual patients and for the nation.
慢性疲劳综合征(CFS)是一种慢性致残性疾病,影响着40万至80万美国人。尽管这种疾病具有致残性,但针对CFS对患者或国民经济的经济影响的研究却很少。方法:我们使用微观模拟方法分析了堪萨斯州威奇托市一项CFS监测研究的数据,并得出了CFS导致的生产力损失估计值。结果:我们估计CFS患者的家庭生产力下降了37%,劳动力生产力下降了54%。美国每年因生产力损失的总价值为91亿美元,这相当于每位CFS患者约2万美元,或约为此综合征患者家庭和劳动力生产力平均值的一半。结论:CFS导致的生产力损失在个体层面以及相对于其他主要疾病的全国估计值而言都相当可观。CFS导致的全国生产力损失与消化系统、免疫系统和神经系统疾病以及皮肤病造成的损失相当。负担程度表明,继续开展研究以确定CFS的病因和潜在治疗方法,可为个体患者和国家带来巨大益处。