Kim So Hyun, Bakko Marlene K, Knowles Don, Borucki Monica K
Animal Disease Research Unit, USDA-ARS, 3003 ADBF, Washington State University, Pullman, WA 99164-6630, USA.
Infect Immun. 2004 Jul;72(7):4318-21. doi: 10.1128/IAI.72.7.4318-4321.2004.
Four-week-old Harlan A/J mice were orally infected with six epidemic and six environmental strains of Listeria monocytogenes. Epidemic strains were significantly more invasive as a group than were environmental strains (P < 0.05), and the intestines of some mice infected with epidemic strains had extensive hemorrhage. Mice inoculated with epidemic strains were significantly more likely to become systemically infected than mice inoculated with environmental strains (P < 0.01).
将四周龄的哈伦A/J小鼠经口感染六株流行株和六株环境株的单核细胞增生李斯特菌。作为一个整体，流行株的侵袭性显著高于环境株（P < 0.05），并且一些感染流行株的小鼠肠道出现广泛出血。接种流行株的小鼠比接种环境株的小鼠更易发生全身感染（P < 0.01）。
