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小鼠经胃内接种后,单核细胞增生李斯特菌分离株感染性的差异

Variation in the infectivity of Listeria monocytogenes isolates following intragastric inoculation of mice.

作者信息

Barbour A H, Rampling A, Hormaeche C E

机构信息

Department of Pathology, University of Cambridge, Cambridge, England.

出版信息

Infect Immun. 2001 Jul;69(7):4657-60. doi: 10.1128/IAI.69.7.4657-4660.2001.

Abstract

The infectivities of 66 Listeria monocytogenes isolates were assessed by intragastric inoculation of mice. Eight were poorly infective. Serovars 4b and 1/2 were more infective than serovars 3 and 4nonb. A noninfective isolate was cleared more rapidly from the cecum than were infective isolates, suggesting that survival in the gut may relate to infectivity.

摘要

通过给小鼠进行胃内接种来评估66株单核细胞增生李斯特菌分离株的感染性。其中8株感染性较差。血清型4b和1/2比血清型3和4非b的感染性更强。一株非感染性分离株从盲肠清除的速度比感染性分离株更快,这表明在肠道中的存活可能与感染性有关。

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