Heinig Matthias, Frishman Dmitrij
Department of Genome Oriented Bioinformatics, Technical University of Munich, Wissenschaftszentrum Weihenstephan, 85354 Freising, Germany.
Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W500-2. doi: 10.1093/nar/gkh429.
STRIDE is a software tool for secondary structure assignment from atomic resolution protein structures. It implements a knowledge-based algorithm that makes combined use of hydrogen bond energy and statistically derived backbone torsional angle information and is optimized to return resulting assignments in maximal agreement with crystallographers' designations. The STRIDE web server provides access to this tool and allows visualization of the secondary structure, as well as contact and Ramachandran maps for any file uploaded by the user with atomic coordinates in the Protein Data Bank (PDB) format. A searchable database of STRIDE assignments for the latest PDB release is also provided. The STRIDE server is accessible from http://webclu.bio.wzw.tum.de/stride/.
STRIDE是一种用于从原子分辨率蛋白质结构进行二级结构分配的软件工具。它实现了一种基于知识的算法,该算法结合使用氢键能量和统计得出的主链扭转角信息,并经过优化,以使所得分配结果与晶体学家的指定结果最大程度地一致。STRIDE网络服务器提供对该工具的访问,并允许可视化二级结构,以及为用户上传的任何具有蛋白质数据库(PDB)格式原子坐标的文件生成接触图和拉马钱德兰图。还提供了最新PDB版本的STRIDE分配结果的可搜索数据库。可通过http://webclu.bio.wzw.tum.de/stride/访问STRIDE服务器。