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下肢浅静脉血栓形成:危险因素、复发情况及抗凝作用分析

Superficial venous thrombosis of the lower extremities: analysis of risk factors, and recurrence and role of anticoagulation.

作者信息

Gorty Satya, Patton-Adkins Jeanne, DaLanno Michelle, Starr Jean, Dean Steven, Satiani Bhagwan

机构信息

Division of Vascular Surgery & Peripheral Vascular Laboratory, The Ohio State University College of Medicine, Columbus, OH, USA.

出版信息

Vasc Med. 2004 Feb;9(1):1-6. doi: 10.1191/1358863x04vm516oa.

DOI:10.1191/1358863x04vm516oa
PMID:15230481
Abstract

Superficial venous thrombosis (SVT) of the lower extremities is a common ailment seen in outpatient offices of vascular medicine and surgery practices. This study of 60 consecutive outpatients was carried out to examine the incidence of concomitant deep venous thrombosis (DVT), risk factors associated with SVT, recurrence of SVT and/or new DVT, and the role of anticoagulant therapy in the prevention of recurrence. Concomitant SVT and DVT (13%) were significantly less likely to be present in patients with varicose veins as compared to patients without varicose veins (p < 0.04) and more likely to be present in patients with a previous history of DVT (p < 0.02). Fifteen patients (25%) developed either recurrent SVT or new DVT, with two patients developing both SVT and DVT. The absence of varicose veins and the presence of a hypercoagulable condition (n = 12) appeared to influence the development of new DVT but not the recurrence of SVT. Recurrent SVT was much more likely in patients with thrombosis of the tributaries (p < 0.0008). New DVT was seen significantly less frequently in patients on anticoagulants (p < 0.02).

摘要

下肢浅静脉血栓形成(SVT)是血管医学和外科门诊常见的病症。本研究对60例连续门诊患者进行,以检查合并深静脉血栓形成(DVT)的发生率、与SVT相关的危险因素、SVT和/或新发DVT的复发情况,以及抗凝治疗在预防复发中的作用。与无静脉曲张的患者相比,静脉曲张患者合并SVT和DVT的可能性显著降低(p < 0.04),而既往有DVT病史的患者合并SVT和DVT的可能性更高(p < 0.02)。15例患者(25%)出现复发性SVT或新发DVT,其中2例患者同时出现SVT和DVT。无静脉曲张和存在高凝状态(n = 12)似乎影响新发DVT的发生,但不影响SVT的复发。分支静脉血栓形成的患者复发性SVT的可能性要高得多(p < 0.0008)。接受抗凝治疗的患者中,新发DVT的发生率明显较低(p < 0.02)。

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