Tuinman Marrit A, Fleer Joke, Hoekstra Harald J, Sleijfer Dirk Th, Hoekstra-Weebers Josette E H M
Department of Surgical Oncology, Groningen University Hospital, P.O. Box 30-001, Groningen 9700 RB, The Netherlands.
Eur J Cancer. 2004 Jul;40(11):1696-703. doi: 10.1016/j.ejca.2004.03.020.
The aim of this study was to gain insight into the quality of life (QoL) and stress response of female spouses of men cured of testicular cancer in the long-term. Time since treatment completion varied from 0.5 to 23.8 years. Two hundred and fifty nine testicular cancer survivors and their spouses completed the Dutch version of the MOS Short Form (SF)-36 and the Impact of Event Scale. QoL data from a reference group of women were used for comparison. Spouses who had relationship with the testicular cancer survivor before the diagnosis (spouses during testicular cancer) had better functioning scores than the reference group, especially with respect to the physical QoL domains. Spouses who had started a relationship after treatment (spouses after testicular cancer) experienced more problems with psychological QoL domains than spouses during testicular cancer and than the reference group. The stress response of spouses during testicular cancer was related to that of the testicular cancer survivors and to the extent of treatment they had received. Although stress response levels were low, spouses during testicular cancer reported more stress response than the testicular cancer survivors. Time since completion of treatment did not affect QoL or stress response. This study showed that spouses during testicular cancer had a good QoL and little stress response. Functioning of spouses after testicular cancer was poorer with respect to various QoL domains, particularly the psychological measures.
本研究旨在深入了解睾丸癌治愈男性的女性配偶的长期生活质量(QoL)和应激反应。治疗结束后的时间从0.5年到23.8年不等。259名睾丸癌幸存者及其配偶完成了荷兰版的医学结局研究简明健康调查(SF-36)和事件影响量表。来自女性参照组的生活质量数据用于比较。在诊断前就与睾丸癌幸存者有关系的配偶(睾丸癌患病期间的配偶)功能评分高于参照组,尤其是在身体生活质量领域。在治疗后开始建立关系的配偶(睾丸癌康复后的配偶)在心理生活质量领域比睾丸癌患病期间的配偶以及参照组经历了更多问题。睾丸癌患病期间配偶的应激反应与睾丸癌幸存者的应激反应以及她们所接受治疗的程度有关。虽然应激反应水平较低,但睾丸癌患病期间的配偶报告的应激反应比睾丸癌幸存者更多。治疗结束后的时间并未影响生活质量或应激反应。本研究表明,睾丸癌患病期间的配偶生活质量良好,应激反应较小。睾丸癌康复后的配偶在各个生活质量领域,尤其是心理指标方面,功能较差。