Dalecki Diane
Department of Biomedical Engineering and the Rochester Center for Biomedical Ultrasound, University of Rochester, Rochester, New York 14627, USA.
Annu Rev Biomed Eng. 2004;6:229-48. doi: 10.1146/annurev.bioeng.6.040803.140126.
Ultrasound is used widely in medicine as both a diagnostic and therapeutic tool. Through both thermal and nonthermal mechanisms, ultrasound can produce a variety of biological effects in tissues in vitro and in vivo. This chapter provides an overview of the fundamentals of key nonthermal mechanisms for the interaction of ultrasound with biological tissues. Several categories of mechanical bioeffects of ultrasound are then reviewed to provide insight on the range of ultrasound bioeffects in vivo, the relevance of these effects to diagnostic imaging, and the potential application of mechanical bioeffects to the design of new therapeutic applications of ultrasound in medicine.
超声作为一种诊断和治疗工具在医学中被广泛应用。通过热机制和非热机制,超声可在体外和体内组织中产生多种生物学效应。本章概述了超声与生物组织相互作用的关键非热机制的基本原理。随后回顾了超声的几类机械生物效应,以深入了解体内超声生物效应的范围、这些效应与诊断成像的相关性,以及机械生物效应在医学超声新治疗应用设计中的潜在应用。