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与组织修复和纤维化诱导相关的肺损伤的细胞和分子反应。

Cellular and molecular responses to lung injury in relation to induction of tissue repair and fibrosis.

作者信息

Finkelstein J N, Horowitz S, Sinkin R A, Ryan R M

机构信息

Department of Pediatrics (Neonatology), Strong Children's Research Center, Rochester, New York.

出版信息

Clin Perinatol. 1992 Sep;19(3):603-20.

PMID:1526074
Abstract

Those factors that determine whether tissue injury is followed by regeneration and repair or irreversible destruction and fibrosis are only now being elucidated. This article examines the lung's response to injury, the prominent role of polypeptide growth factors and cytokines in directing tissue responses, and the effects of injury on cell-specific expression of a number of genes.

摘要

那些决定组织损伤后是发生再生和修复还是不可逆破坏及纤维化的因素,直到现在才得以阐明。本文探讨了肺对损伤的反应、多肽生长因子和细胞因子在指导组织反应中的突出作用,以及损伤对许多基因细胞特异性表达的影响。

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Antioxidants in neonatal lung disease.新生儿肺部疾病中的抗氧化剂
Arch Dis Child Fetal Neonatal Ed. 1995 Sep;73(2):F112-7. doi: 10.1136/fn.73.2.f112.