Hopstaken R M, Witbraad T, van Engelshoven J M A, Dinant G J
Department of General Practice, Care and Public Health Research Institute (Caphri), Maastricht University and University Hospital Maastricht, Maastricht, The Netherlands.
Clin Radiol. 2004 Aug;59(8):743-52. doi: 10.1016/j.crad.2004.01.011.
To assess inter-observer variation in the interpretation of chest radiographs of individuals with pneumonia versus those without pneumonia.
Chest radiographs of out-patients with a lower respiratory tract infection (LRTI) were assessed for the presence of infiltrates by radiologists from three local hospitals and were reassessed by one university hospital radiologist. Various measures of inter-observer agreement were calculated.
The observed proportional agreement was 218 in 243 patients (89.7%). Kappa was 0.53 (moderate agreement) with a 95% confidence interval of 0.37 to 0.69. The observed positive agreement (59%) was much lower than for negative agreement (94%). Kappa was considerably lower, if chronic obstructive pulmonary disease was present (kappa = 0.20) or Streptococcus pneumoniae (kappa = -0.29) was the infective agent.
The overall inter-observer agreement adjusted for chance was moderate. Inter-observer agreement in cases with pneumonia was much worse than the agreement in negative (i.e. non-pneumonia) cases. A general practitioner's selection of patients with a higher chance of having pneumonia for chest radiography would thus not improve the observer agreement.
评估观察者之间对肺炎患者与非肺炎患者胸部X光片解读的差异。
来自三家当地医院的放射科医生对患有下呼吸道感染(LRTI)的门诊患者的胸部X光片进行浸润情况评估,并由一名大学医院的放射科医生重新评估。计算了观察者之间一致性的各种指标。
在243例患者中,观察到的比例一致性为218例(89.7%)。Kappa值为0.53(中度一致性),95%置信区间为0.37至0.69。观察到的阳性一致性(59%)远低于阴性一致性(94%)。如果存在慢性阻塞性肺疾病(kappa = 0.20)或感染病原体为肺炎链球菌(kappa = -0.29),Kappa值会显著降低。
校正机遇后的观察者间总体一致性为中度。肺炎病例中的观察者间一致性比阴性(即非肺炎)病例中的一致性差得多。因此,全科医生选择肺炎可能性较高的患者进行胸部X光检查并不能提高观察者间的一致性。